SPDL1 overexpression was associated with poor prognosis and immune status in HCC through in vitro experiment and bioinformatics analysis

SPDL1 overexpression was associated with poor prognosis and immune status in HCC through in vitro experiment and bioinformatics analysis

Abstract Background Numerous studies have established a strong link between the overexpression of spindle apparatus coiled-coil protein 1 (SPDL1) and cancer progression. However, the role of SPDL1 in hepatocellular carcinoma (HCC) remains unconfirmed. Methods The level of SPDL1 in HCC and its potent...

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Bibliographic Details
Main Authors: Ying-Ming Xu, Bo-Hua You, Ming Chen, Tian-Ping Xiong, Lin Shi, Qin Wei, Zhong-An Wang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
SPDL1
Hepatocellular carcinoma
Biomarkers
Nomogram
Bioinformatics
Online Access:https://doi.org/10.1007/s12672-025-03089-8
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