Detection of Peripheral Ventilation Inhomogeneity in Smokers

BACKGROUND: In smokers, ‘small airways’ narrowing alters the conventional, vital capacity single breath washout (SBWVC). Although, in some studies, the test predicts smokers at risk of developing chronic airflow limitation, its wide variability partly explains its poor positive predictive value. An...

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Main Authors: DJ Cotton, JT Mink, BL Graham
Format: Article
Language:English
Published: Wiley 1997-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/1997/234268
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author DJ Cotton
JT Mink
BL Graham
author_facet DJ Cotton
JT Mink
BL Graham
author_sort DJ Cotton
collection DOAJ
description BACKGROUND: In smokers, ‘small airways’ narrowing alters the conventional, vital capacity single breath washout (SBWVC). Although, in some studies, the test predicts smokers at risk of developing chronic airflow limitation, its wide variability partly explains its poor positive predictive value. An alternative explanation for the test’s poor predictive value is that it may not accurately reflect small airway narrowing in the lung periphery.
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series Canadian Respiratory Journal
spelling doaj-art-8e5e12889a0f438eb337f3a5b009e7b92025-02-03T01:31:19ZengWileyCanadian Respiratory Journal1198-22411997-01-0141273310.1155/1997/234268Detection of Peripheral Ventilation Inhomogeneity in SmokersDJ Cotton0JT Mink1BL Graham2Respiratory Division, Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, CanadaRespiratory Division, Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, CanadaRespiratory Division, Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, CanadaBACKGROUND: In smokers, ‘small airways’ narrowing alters the conventional, vital capacity single breath washout (SBWVC). Although, in some studies, the test predicts smokers at risk of developing chronic airflow limitation, its wide variability partly explains its poor positive predictive value. An alternative explanation for the test’s poor predictive value is that it may not accurately reflect small airway narrowing in the lung periphery.http://dx.doi.org/10.1155/1997/234268
spellingShingle DJ Cotton
JT Mink
BL Graham
Detection of Peripheral Ventilation Inhomogeneity in Smokers
Canadian Respiratory Journal
title Detection of Peripheral Ventilation Inhomogeneity in Smokers
title_full Detection of Peripheral Ventilation Inhomogeneity in Smokers
title_fullStr Detection of Peripheral Ventilation Inhomogeneity in Smokers
title_full_unstemmed Detection of Peripheral Ventilation Inhomogeneity in Smokers
title_short Detection of Peripheral Ventilation Inhomogeneity in Smokers
title_sort detection of peripheral ventilation inhomogeneity in smokers
url http://dx.doi.org/10.1155/1997/234268
work_keys_str_mv AT djcotton detectionofperipheralventilationinhomogeneityinsmokers
AT jtmink detectionofperipheralventilationinhomogeneityinsmokers
AT blgraham detectionofperipheralventilationinhomogeneityinsmokers