Colistin induced neurotoxicity with bulbar palsy. A case report and literature review
Colistin, a polymyxin antibiotic, is increasingly used to manage infections caused by multidrug-resistant gram-negative bacteria. This case report documents the occurrence of colistin-induced neurotoxicity manifesting as bulbar palsy in a 38-year-old male with a complex medical history. The patient,...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | IDCases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250924001926 |
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| _version_ | 1850168286869716992 |
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| author | Mohamed Kamal Mansour Ali Mohamed Raju Raghunathan |
| author_facet | Mohamed Kamal Mansour Ali Mohamed Raju Raghunathan |
| author_sort | Mohamed Kamal Mansour |
| collection | DOAJ |
| description | Colistin, a polymyxin antibiotic, is increasingly used to manage infections caused by multidrug-resistant gram-negative bacteria. This case report documents the occurrence of colistin-induced neurotoxicity manifesting as bulbar palsy in a 38-year-old male with a complex medical history. The patient, presenting with septic shock secondary to a diabetic foot ulcer, was administered colistin and meropenem, leading to a progressive onset of neurological symptoms. The timely discontinuation of colistin resulted in the complete resolution of neurotoxicity. |
| format | Article |
| id | doaj-art-8e5bf972de78485e938fdc4e56ced68f |
| institution | OA Journals |
| issn | 2214-2509 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj-art-8e5bf972de78485e938fdc4e56ced68f2025-08-20T02:20:59ZengElsevierIDCases2214-25092024-01-0138e0211610.1016/j.idcr.2024.e02116Colistin induced neurotoxicity with bulbar palsy. A case report and literature reviewMohamed Kamal Mansour0Ali Mohamed1Raju Raghunathan2Corresponding author.; Hospital Medicine Department, Integrated Hospital Care Institute, Cleveland Clinic Abu-Dhabi, PO BOX: 112412, Abu-Dhabi, United Arab EmiratesHospital Medicine Department, Integrated Hospital Care Institute, Cleveland Clinic Abu-Dhabi, PO BOX: 112412, Abu-Dhabi, United Arab EmiratesHospital Medicine Department, Integrated Hospital Care Institute, Cleveland Clinic Abu-Dhabi, PO BOX: 112412, Abu-Dhabi, United Arab EmiratesColistin, a polymyxin antibiotic, is increasingly used to manage infections caused by multidrug-resistant gram-negative bacteria. This case report documents the occurrence of colistin-induced neurotoxicity manifesting as bulbar palsy in a 38-year-old male with a complex medical history. The patient, presenting with septic shock secondary to a diabetic foot ulcer, was administered colistin and meropenem, leading to a progressive onset of neurological symptoms. The timely discontinuation of colistin resulted in the complete resolution of neurotoxicity.http://www.sciencedirect.com/science/article/pii/S2214250924001926ColistinNeurotoxicityMulti drug resistant organisms (MDR) |
| spellingShingle | Mohamed Kamal Mansour Ali Mohamed Raju Raghunathan Colistin induced neurotoxicity with bulbar palsy. A case report and literature review IDCases Colistin Neurotoxicity Multi drug resistant organisms (MDR) |
| title | Colistin induced neurotoxicity with bulbar palsy. A case report and literature review |
| title_full | Colistin induced neurotoxicity with bulbar palsy. A case report and literature review |
| title_fullStr | Colistin induced neurotoxicity with bulbar palsy. A case report and literature review |
| title_full_unstemmed | Colistin induced neurotoxicity with bulbar palsy. A case report and literature review |
| title_short | Colistin induced neurotoxicity with bulbar palsy. A case report and literature review |
| title_sort | colistin induced neurotoxicity with bulbar palsy a case report and literature review |
| topic | Colistin Neurotoxicity Multi drug resistant organisms (MDR) |
| url | http://www.sciencedirect.com/science/article/pii/S2214250924001926 |
| work_keys_str_mv | AT mohamedkamalmansour colistininducedneurotoxicitywithbulbarpalsyacasereportandliteraturereview AT alimohamed colistininducedneurotoxicitywithbulbarpalsyacasereportandliteraturereview AT rajuraghunathan colistininducedneurotoxicitywithbulbarpalsyacasereportandliteraturereview |