Anaphylactoid Purpura Associated with Streptococcal Cellulitis: A Case Report and Literature Review

A 54-year-old Japanese man noticed painful swelling and redness of his left leg. He was admitted for treatment of cellulitis, which was accompanied with increased anti-streptolysin O and anti-streptokinase titers in his clinical course. After Piperacillin/Tazobactam administration, the skin lesion r...

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Main Authors: Yuko Saito, Susumu Ookawara, Hisataka Uchima, Takeshi Ishida, Masafumi Kakei, Hitoshi Sugawara
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2017/5960898
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author Yuko Saito
Susumu Ookawara
Hisataka Uchima
Takeshi Ishida
Masafumi Kakei
Hitoshi Sugawara
author_facet Yuko Saito
Susumu Ookawara
Hisataka Uchima
Takeshi Ishida
Masafumi Kakei
Hitoshi Sugawara
author_sort Yuko Saito
collection DOAJ
description A 54-year-old Japanese man noticed painful swelling and redness of his left leg. He was admitted for treatment of cellulitis, which was accompanied with increased anti-streptolysin O and anti-streptokinase titers in his clinical course. After Piperacillin/Tazobactam administration, the skin lesion resolved. However, the patient then developed arthritis, palpable purpura, and intermittent abdominal pain, later found to be secondary to a severe duodenal ulcer. He was diagnosed with cellulitis-associated anaphylactoid purpura and was given prednisolone, which dramatically improved his symptoms. The anaphylactoid purpura was likely caused by Streptococcus-induced cellulitis, which was successfully treated with prednisolone. Association between these diseases is rare.
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spelling doaj-art-8e5af338ccae4124b68f4eacf54f4eec2025-08-20T02:09:22ZengWileyCase Reports in Medicine1687-96271687-96352017-01-01201710.1155/2017/59608985960898Anaphylactoid Purpura Associated with Streptococcal Cellulitis: A Case Report and Literature ReviewYuko Saito0Susumu Ookawara1Hisataka Uchima2Takeshi Ishida3Masafumi Kakei4Hitoshi Sugawara5Division of General Medicine, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama-City, Saitama-ken 330-8503, JapanDivision of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama-City, Saitama-ken 330-8503, JapanDepartment of Pathology, Saitama Citizens Medical Center, 299-1 Shimane, Nishi-ku, Saitama-City, Saitama-ken 331-0054, JapanDepartment of Internal Medicine, Saitama Citizens Medical Center, 299-1 Shimane, Nishi-ku, Saitama-City, Saitama-ken 331-0054, JapanDepartment of Internal Medicine, Saitama Citizens Medical Center, 299-1 Shimane, Nishi-ku, Saitama-City, Saitama-ken 331-0054, JapanDivision of General Medicine, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama-City, Saitama-ken 330-8503, JapanA 54-year-old Japanese man noticed painful swelling and redness of his left leg. He was admitted for treatment of cellulitis, which was accompanied with increased anti-streptolysin O and anti-streptokinase titers in his clinical course. After Piperacillin/Tazobactam administration, the skin lesion resolved. However, the patient then developed arthritis, palpable purpura, and intermittent abdominal pain, later found to be secondary to a severe duodenal ulcer. He was diagnosed with cellulitis-associated anaphylactoid purpura and was given prednisolone, which dramatically improved his symptoms. The anaphylactoid purpura was likely caused by Streptococcus-induced cellulitis, which was successfully treated with prednisolone. Association between these diseases is rare.http://dx.doi.org/10.1155/2017/5960898
spellingShingle Yuko Saito
Susumu Ookawara
Hisataka Uchima
Takeshi Ishida
Masafumi Kakei
Hitoshi Sugawara
Anaphylactoid Purpura Associated with Streptococcal Cellulitis: A Case Report and Literature Review
Case Reports in Medicine
title Anaphylactoid Purpura Associated with Streptococcal Cellulitis: A Case Report and Literature Review
title_full Anaphylactoid Purpura Associated with Streptococcal Cellulitis: A Case Report and Literature Review
title_fullStr Anaphylactoid Purpura Associated with Streptococcal Cellulitis: A Case Report and Literature Review
title_full_unstemmed Anaphylactoid Purpura Associated with Streptococcal Cellulitis: A Case Report and Literature Review
title_short Anaphylactoid Purpura Associated with Streptococcal Cellulitis: A Case Report and Literature Review
title_sort anaphylactoid purpura associated with streptococcal cellulitis a case report and literature review
url http://dx.doi.org/10.1155/2017/5960898
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