Unmasking the hidden threat: a case and review of primary hyperparathyroidism-induced pancreatitis diagnosed in pregnancy

Primary hyperparathyroidism is a very well-documented and understood endocrine pathology that includes the overproduction of parathyroid hormone, leading to an exaggerated effect of hypercalcemia. However, its prevalence leading to pancreatitis, specifically in pregnant patients, is underreported an...

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Main Authors: Nizar Alyassin, Ruba Habib, Michael Pelidis, Patrick Michael
Format: Article
Language:English
Published: SMC MEDIA SRL 2025-06-01
Series:European Journal of Case Reports in Internal Medicine
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Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/5546
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author Nizar Alyassin
Ruba Habib
Michael Pelidis
Patrick Michael
author_facet Nizar Alyassin
Ruba Habib
Michael Pelidis
Patrick Michael
author_sort Nizar Alyassin
collection DOAJ
description Primary hyperparathyroidism is a very well-documented and understood endocrine pathology that includes the overproduction of parathyroid hormone, leading to an exaggerated effect of hypercalcemia. However, its prevalence leading to pancreatitis, specifically in pregnant patients, is underreported and widely undiagnosed. In this case, we present a case of a 23-year-old female in her second pregnancy who presented with pancreatitis after already being treated and diagnosed with pancreatitis in her first pregnancy. It was later discovered that this patient had a nodule believed to be a parathyroid adenoma. We believe this parathyroid adenoma alone could have gone unnoticed, but with concurrent changes and physiology of pregnancy, caused a significant burden of pancreatitis on our patient, not only in one pregnancy, but in both of her pregnancies.
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series European Journal of Case Reports in Internal Medicine
spelling doaj-art-8e58d56dae2f450db11c726e0c8140182025-08-20T03:30:40ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942025-06-0110.12890/2025_0055465081Unmasking the hidden threat: a case and review of primary hyperparathyroidism-induced pancreatitis diagnosed in pregnancyNizar Alyassin0Ruba Habib1Michael Pelidis2Patrick Michael3Department of Internal Medicine, St. Joseph’s Regional Medical Center, Paterson, USADepartment of Internal Medicine, St. Joseph’s Regional Medical Center, Paterson, USADepartment of Internal Medicine, St. Joseph’s Regional Medical Center, Paterson, USADepartment of Internal Medicine, St. Joseph’s Regional Medical Center, Paterson, USAPrimary hyperparathyroidism is a very well-documented and understood endocrine pathology that includes the overproduction of parathyroid hormone, leading to an exaggerated effect of hypercalcemia. However, its prevalence leading to pancreatitis, specifically in pregnant patients, is underreported and widely undiagnosed. In this case, we present a case of a 23-year-old female in her second pregnancy who presented with pancreatitis after already being treated and diagnosed with pancreatitis in her first pregnancy. It was later discovered that this patient had a nodule believed to be a parathyroid adenoma. We believe this parathyroid adenoma alone could have gone unnoticed, but with concurrent changes and physiology of pregnancy, caused a significant burden of pancreatitis on our patient, not only in one pregnancy, but in both of her pregnancies.https://www.ejcrim.com/index.php/EJCRIM/article/view/5546primary hyperparathyroidismpancreatitispancreatitis in pregnancyparathyroid hormonehypercalcemia
spellingShingle Nizar Alyassin
Ruba Habib
Michael Pelidis
Patrick Michael
Unmasking the hidden threat: a case and review of primary hyperparathyroidism-induced pancreatitis diagnosed in pregnancy
European Journal of Case Reports in Internal Medicine
primary hyperparathyroidism
pancreatitis
pancreatitis in pregnancy
parathyroid hormone
hypercalcemia
title Unmasking the hidden threat: a case and review of primary hyperparathyroidism-induced pancreatitis diagnosed in pregnancy
title_full Unmasking the hidden threat: a case and review of primary hyperparathyroidism-induced pancreatitis diagnosed in pregnancy
title_fullStr Unmasking the hidden threat: a case and review of primary hyperparathyroidism-induced pancreatitis diagnosed in pregnancy
title_full_unstemmed Unmasking the hidden threat: a case and review of primary hyperparathyroidism-induced pancreatitis diagnosed in pregnancy
title_short Unmasking the hidden threat: a case and review of primary hyperparathyroidism-induced pancreatitis diagnosed in pregnancy
title_sort unmasking the hidden threat a case and review of primary hyperparathyroidism induced pancreatitis diagnosed in pregnancy
topic primary hyperparathyroidism
pancreatitis
pancreatitis in pregnancy
parathyroid hormone
hypercalcemia
url https://www.ejcrim.com/index.php/EJCRIM/article/view/5546
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AT michaelpelidis unmaskingthehiddenthreatacaseandreviewofprimaryhyperparathyroidisminducedpancreatitisdiagnosedinpregnancy
AT patrickmichael unmaskingthehiddenthreatacaseandreviewofprimaryhyperparathyroidisminducedpancreatitisdiagnosedinpregnancy