Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress

Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress

Increasing evidence has demonstrated that oxidative stress impairs oocyte maturation and embryonic development. Conventionally, antioxidants have been applied in vitro systems to improve oocyte maturation and blastocyst rates. Formononetin (FMN) is a flavonoid that has been shown to have various pha...

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Bibliographic Details
Main Authors: Na Wang, Han Yang, Yelei Chen, Hekun Wang, Chaorui Wang, Jianglin Fan, Yajie Chen, Yinghua Li, Maobi Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
formononetin
mitochondrial function
oxidative stress
Nrf2/Keap1
autophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1520429/full
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