EFFECT OF LISINOPRIL AND ENALAPRIL ON QUALITY OF LIFE AND BLOOD PRESSURE DAILY PROFILE IN PATIENTS WITH STABLE ARTERIAL HYPERTENSION.

Aim. To compare effect of long-term treatment with lisinopril and enalapril on quality of life (QL) and blood pressure (BP) daily profile in patients with stable arterial hypertension (AH). Material and methods. Analysis of three studies conducted in our center during last 4 years are presented (tot...

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Main Authors: G. F. Andreeva, A. D. Deev, V. M. Gorbunov
Format: Article
Language:English
Published: Столичная издательская компания 2016-01-01
Series:Рациональная фармакотерапия в кардиологии
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Online Access:https://www.rpcardio.online/jour/article/view/1016
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author G. F. Andreeva
A. D. Deev
V. M. Gorbunov
author_facet G. F. Andreeva
A. D. Deev
V. M. Gorbunov
author_sort G. F. Andreeva
collection DOAJ
description Aim. To compare effect of long-term treatment with lisinopril and enalapril on quality of life (QL) and blood pressure (BP) daily profile in patients with stable arterial hypertension (AH). Material and methods. Analysis of three studies conducted in our center during last 4 years are presented (totally 86 patients were included). Protocol of studies was unified: after wash-out period ambulatory blood pressure monitoring (ABPM) and QL were assessed. Afterwards, patients were switched to active therapy with enalapril or lisinopril. After long-term treatment with these drugs QL and ABPM and QL were assessed again. Results. Both drugs decreased in systolic and diastolic BP, time index and didn't change heart rate and night BP dipping. With lisinopril treatment, significant improvement in physical condition, efficiency at work, psychological profile and capacity for social contacts was observed, while treatment with enalapril positively influenced only on physical condition and intensity of negative psychological profile in patients with stable AH. Conclusion. In patients with stable AH lisinopril had better influence on QL than enalapril. Therapy with both drugs lead to significant decrease in systolic and diastolic BP and didn't change heart rate and night BP dipping.
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series Рациональная фармакотерапия в кардиологии
spelling doaj-art-8e4a4a92f49e4ef5af14360b789fb6132025-08-23T10:00:25ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-01-0122323610.20996/1819-6446-2006-2-2-32-361015EFFECT OF LISINOPRIL AND ENALAPRIL ON QUALITY OF LIFE AND BLOOD PRESSURE DAILY PROFILE IN PATIENTS WITH STABLE ARTERIAL HYPERTENSION.G. F. Andreeva0A. D. Deev1V. M. Gorbunov2State Research Center of Preventive Medicine, RoszdravState Research Center of Preventive Medicine, RoszdravState Research Center of Preventive Medicine, RoszdravAim. To compare effect of long-term treatment with lisinopril and enalapril on quality of life (QL) and blood pressure (BP) daily profile in patients with stable arterial hypertension (AH). Material and methods. Analysis of three studies conducted in our center during last 4 years are presented (totally 86 patients were included). Protocol of studies was unified: after wash-out period ambulatory blood pressure monitoring (ABPM) and QL were assessed. Afterwards, patients were switched to active therapy with enalapril or lisinopril. After long-term treatment with these drugs QL and ABPM and QL were assessed again. Results. Both drugs decreased in systolic and diastolic BP, time index and didn't change heart rate and night BP dipping. With lisinopril treatment, significant improvement in physical condition, efficiency at work, psychological profile and capacity for social contacts was observed, while treatment with enalapril positively influenced only on physical condition and intensity of negative psychological profile in patients with stable AH. Conclusion. In patients with stable AH lisinopril had better influence on QL than enalapril. Therapy with both drugs lead to significant decrease in systolic and diastolic BP and didn't change heart rate and night BP dipping.https://www.rpcardio.online/jour/article/view/1016arterial hypertensionantihypertensive therapyquality of lifelisinoprilambulatory blood pressure monitoring
spellingShingle G. F. Andreeva
A. D. Deev
V. M. Gorbunov
EFFECT OF LISINOPRIL AND ENALAPRIL ON QUALITY OF LIFE AND BLOOD PRESSURE DAILY PROFILE IN PATIENTS WITH STABLE ARTERIAL HYPERTENSION.
Рациональная фармакотерапия в кардиологии
arterial hypertension
antihypertensive therapy
quality of life
lisinopril
ambulatory blood pressure monitoring
title EFFECT OF LISINOPRIL AND ENALAPRIL ON QUALITY OF LIFE AND BLOOD PRESSURE DAILY PROFILE IN PATIENTS WITH STABLE ARTERIAL HYPERTENSION.
title_full EFFECT OF LISINOPRIL AND ENALAPRIL ON QUALITY OF LIFE AND BLOOD PRESSURE DAILY PROFILE IN PATIENTS WITH STABLE ARTERIAL HYPERTENSION.
title_fullStr EFFECT OF LISINOPRIL AND ENALAPRIL ON QUALITY OF LIFE AND BLOOD PRESSURE DAILY PROFILE IN PATIENTS WITH STABLE ARTERIAL HYPERTENSION.
title_full_unstemmed EFFECT OF LISINOPRIL AND ENALAPRIL ON QUALITY OF LIFE AND BLOOD PRESSURE DAILY PROFILE IN PATIENTS WITH STABLE ARTERIAL HYPERTENSION.
title_short EFFECT OF LISINOPRIL AND ENALAPRIL ON QUALITY OF LIFE AND BLOOD PRESSURE DAILY PROFILE IN PATIENTS WITH STABLE ARTERIAL HYPERTENSION.
title_sort effect of lisinopril and enalapril on quality of life and blood pressure daily profile in patients with stable arterial hypertension
topic arterial hypertension
antihypertensive therapy
quality of life
lisinopril
ambulatory blood pressure monitoring
url https://www.rpcardio.online/jour/article/view/1016
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AT vmgorbunov effectoflisinoprilandenalaprilonqualityoflifeandbloodpressuredailyprofileinpatientswithstablearterialhypertension