CHARACTERISTICS OF MYCOBACTERIUM TUBERCULOSIS POPULATION IN KARELIYA REPUBLIC
Goal of the study: genotyping of Mycobacterium tuberculosis strains isolated from pulmonary tuberculosis patients in Kareliya Republic from June 2013 to January 2014.Results. Spoligotyping of 78 M. tuberculosis strains showed that they belonged to families of Beijing (n = 43), T (n = 11), URAL (n =...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2016-08-01
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| Series: | Туберкулез и болезни лёгких |
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| Online Access: | https://www.tibl-journal.com/jour/article/view/917 |
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| author | A. A. Vyazovaya N. S. Solovieva T. V. Sunchalina I. V. Mokrousov V. Yu. Zhuravlev O. V. Narvskaya |
| author_facet | A. A. Vyazovaya N. S. Solovieva T. V. Sunchalina I. V. Mokrousov V. Yu. Zhuravlev O. V. Narvskaya |
| author_sort | A. A. Vyazovaya |
| collection | DOAJ |
| description | Goal of the study: genotyping of Mycobacterium tuberculosis strains isolated from pulmonary tuberculosis patients in Kareliya Republic from June 2013 to January 2014.Results. Spoligotyping of 78 M. tuberculosis strains showed that they belonged to families of Beijing (n = 43), T (n = 11), URAL (n = 10), LAM (n = 8), Haarlem and Х. Eight out of 24 spoligotypes: SIT1 (Beijing); SIT40, SIT52, SIT53 (T); SIT35 и SIT262 (H3/URAL); SIT42 (LAM); SIT50 (Haarlem) were represented by two and more strains. The association between primary multiple resistance and Beijing genotype ofthe mycobacterium was defined, and 43.8% of M. tuberculosis strains of this genotype belonged to В0/W148 cluster which was of the epidemiological and clinical significance. T group was represented by drug susceptible strains only. |
| format | Article |
| id | doaj-art-8e49d3fa81e341d0882797e1c36e7a23 |
| institution | OA Journals |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2016-08-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-8e49d3fa81e341d0882797e1c36e7a232025-08-20T02:15:59ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062016-08-01948485310.21292/2075-1230-2016-94-8-48-53917CHARACTERISTICS OF MYCOBACTERIUM TUBERCULOSIS POPULATION IN KARELIYA REPUBLICA. A. Vyazovaya0N. S. Solovieva1T. V. Sunchalina2I. V. Mokrousov3V. Yu. Zhuravlev4O. V. Narvskaya5Pasteur St. Petersburg Research Institute of Epidemiology and MicrobiologySt. Petersburg Research Institute of PhthisiopulmonologyRepublican TB DispensaryPasteur St. Petersburg Research Institute of Epidemiology and MicrobiologySt. Petersburg Research Institute of PhthisiopulmonologyPasteur St. Petersburg Research Institute of Epidemiology and Microbiology; St. Petersburg Research Institute of PhthisiopulmonologyGoal of the study: genotyping of Mycobacterium tuberculosis strains isolated from pulmonary tuberculosis patients in Kareliya Republic from June 2013 to January 2014.Results. Spoligotyping of 78 M. tuberculosis strains showed that they belonged to families of Beijing (n = 43), T (n = 11), URAL (n = 10), LAM (n = 8), Haarlem and Х. Eight out of 24 spoligotypes: SIT1 (Beijing); SIT40, SIT52, SIT53 (T); SIT35 и SIT262 (H3/URAL); SIT42 (LAM); SIT50 (Haarlem) were represented by two and more strains. The association between primary multiple resistance and Beijing genotype ofthe mycobacterium was defined, and 43.8% of M. tuberculosis strains of this genotype belonged to В0/W148 cluster which was of the epidemiological and clinical significance. T group was represented by drug susceptible strains only.https://www.tibl-journal.com/jour/article/view/917m. tuberculosism. tuberculosiskareliya republicgenotypingbeijing genotype |
| spellingShingle | A. A. Vyazovaya N. S. Solovieva T. V. Sunchalina I. V. Mokrousov V. Yu. Zhuravlev O. V. Narvskaya CHARACTERISTICS OF MYCOBACTERIUM TUBERCULOSIS POPULATION IN KARELIYA REPUBLIC Туберкулез и болезни лёгких m. tuberculosis m. tuberculosis kareliya republic genotyping beijing genotype |
| title | CHARACTERISTICS OF MYCOBACTERIUM TUBERCULOSIS POPULATION IN KARELIYA REPUBLIC |
| title_full | CHARACTERISTICS OF MYCOBACTERIUM TUBERCULOSIS POPULATION IN KARELIYA REPUBLIC |
| title_fullStr | CHARACTERISTICS OF MYCOBACTERIUM TUBERCULOSIS POPULATION IN KARELIYA REPUBLIC |
| title_full_unstemmed | CHARACTERISTICS OF MYCOBACTERIUM TUBERCULOSIS POPULATION IN KARELIYA REPUBLIC |
| title_short | CHARACTERISTICS OF MYCOBACTERIUM TUBERCULOSIS POPULATION IN KARELIYA REPUBLIC |
| title_sort | characteristics of mycobacterium tuberculosis population in kareliya republic |
| topic | m. tuberculosis m. tuberculosis kareliya republic genotyping beijing genotype |
| url | https://www.tibl-journal.com/jour/article/view/917 |
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