Association of Hematological and Lipid Profile Parameters with Respiratory Functions in Class I Obese Young Adults
Background: Among the different forms of obesity, abdominal obesity has shown powerful associations with cardiovascular and respiratory issues. This study aimed to evaluate the association of hematological and lipid profile parameters with respiratory functions in Class I obese young adults. Meth...
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ziauddin University
2025-04-01
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| Series: | Pakistan Journal of Medicine and Dentistry |
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| Online Access: | https://ojs.zu.edu.pk/pjmd/article/view/3632 |
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| author | Salah Uddin Farhen Malik |
| author_facet | Salah Uddin Farhen Malik |
| author_sort | Salah Uddin |
| collection | DOAJ |
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Background: Among the different forms of obesity, abdominal obesity has shown powerful associations with cardiovascular and respiratory issues. This study aimed to evaluate the association of hematological and lipid profile parameters with respiratory functions in Class I obese young adults.
Method: This cross-sectional, multicenter study was carried out at Isra University Hospital, Memon Medical Complex, and Rajputana Hospital in Hyderabad between April 2021 and July 2024. 376 Young adults within the age bracket of 18-35 years, both males and females, were recruited in the study via a convenience sampling technique. The anthropometric measurements of participants were taken. Afterward, fasting blood samples were collected for biochemical analysis. Lipid profiles were assessed using the Micro Lab 300 machine. The data collected from respondents were entered and analyzed using MedCalc Statistical Software. The Pearson correlation test was applied to measure the strength of the association between variables. P level <0.05 was considered significant.
Results: The mean age of male and female participants was 26.60±4.41 and 26.11±3.28 years, respectively. The inverse relation between lung capacity and lipid profile was observed (p<0.005), indicating reduced lung capacity with higher cholesterol. Hemoglobin also correlates negatively with VC (r = -0.32, p = 0.0003), FVC (r = -0.26, p = 0.0029), and TLC (r = -0.33, p = 0.002), suggesting increased blood viscosity may impair oxygen transport.
Conclusion: The findings suggest a fair to moderate correlation between Hematological and Lipid profile parameters with respiratory functions in class I obese young adults.
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| format | Article |
| id | doaj-art-8e48f50bdf4e4b3494b583f154bdd938 |
| institution | OA Journals |
| issn | 2313-7371 2308-2593 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | ziauddin University |
| record_format | Article |
| series | Pakistan Journal of Medicine and Dentistry |
| spelling | doaj-art-8e48f50bdf4e4b3494b583f154bdd9382025-08-20T02:11:37Zengziauddin UniversityPakistan Journal of Medicine and Dentistry2313-73712308-25932025-04-0114210.36283/ziun-pjmd14-2/023Association of Hematological and Lipid Profile Parameters with Respiratory Functions in Class I Obese Young AdultsSalah Uddin0https://orcid.org/0009-0009-6515-5744Farhen Malik1https://orcid.org/0009-0008-2210-2899Isra University, Hyderabad, PakistanIsra University, Hyderabad, Pakistan Background: Among the different forms of obesity, abdominal obesity has shown powerful associations with cardiovascular and respiratory issues. This study aimed to evaluate the association of hematological and lipid profile parameters with respiratory functions in Class I obese young adults. Method: This cross-sectional, multicenter study was carried out at Isra University Hospital, Memon Medical Complex, and Rajputana Hospital in Hyderabad between April 2021 and July 2024. 376 Young adults within the age bracket of 18-35 years, both males and females, were recruited in the study via a convenience sampling technique. The anthropometric measurements of participants were taken. Afterward, fasting blood samples were collected for biochemical analysis. Lipid profiles were assessed using the Micro Lab 300 machine. The data collected from respondents were entered and analyzed using MedCalc Statistical Software. The Pearson correlation test was applied to measure the strength of the association between variables. P level <0.05 was considered significant. Results: The mean age of male and female participants was 26.60±4.41 and 26.11±3.28 years, respectively. The inverse relation between lung capacity and lipid profile was observed (p<0.005), indicating reduced lung capacity with higher cholesterol. Hemoglobin also correlates negatively with VC (r = -0.32, p = 0.0003), FVC (r = -0.26, p = 0.0029), and TLC (r = -0.33, p = 0.002), suggesting increased blood viscosity may impair oxygen transport. Conclusion: The findings suggest a fair to moderate correlation between Hematological and Lipid profile parameters with respiratory functions in class I obese young adults. https://ojs.zu.edu.pk/pjmd/article/view/3632ObesityLipidLung FunctionBiomarker |
| spellingShingle | Salah Uddin Farhen Malik Association of Hematological and Lipid Profile Parameters with Respiratory Functions in Class I Obese Young Adults Pakistan Journal of Medicine and Dentistry Obesity Lipid Lung Function Biomarker |
| title | Association of Hematological and Lipid Profile Parameters with Respiratory Functions in Class I Obese Young Adults |
| title_full | Association of Hematological and Lipid Profile Parameters with Respiratory Functions in Class I Obese Young Adults |
| title_fullStr | Association of Hematological and Lipid Profile Parameters with Respiratory Functions in Class I Obese Young Adults |
| title_full_unstemmed | Association of Hematological and Lipid Profile Parameters with Respiratory Functions in Class I Obese Young Adults |
| title_short | Association of Hematological and Lipid Profile Parameters with Respiratory Functions in Class I Obese Young Adults |
| title_sort | association of hematological and lipid profile parameters with respiratory functions in class i obese young adults |
| topic | Obesity Lipid Lung Function Biomarker |
| url | https://ojs.zu.edu.pk/pjmd/article/view/3632 |
| work_keys_str_mv | AT salahuddin associationofhematologicalandlipidprofileparameterswithrespiratoryfunctionsinclassiobeseyoungadults AT farhenmalik associationofhematologicalandlipidprofileparameterswithrespiratoryfunctionsinclassiobeseyoungadults |