Association of Hematological and Lipid Profile Parameters with Respiratory Functions in Class I Obese Young Adults

Background: Among the different forms of obesity, abdominal obesity has shown powerful associations with cardiovascular and respiratory issues. This study aimed to evaluate the association of hematological and lipid profile parameters with respiratory functions in Class I obese young adults. Meth...

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Bibliographic Details
Main Authors: Salah Uddin, Farhen Malik
Format: Article
Language:English
Published: ziauddin University 2025-04-01
Series:Pakistan Journal of Medicine and Dentistry
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Online Access:https://ojs.zu.edu.pk/pjmd/article/view/3632
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Summary:Background: Among the different forms of obesity, abdominal obesity has shown powerful associations with cardiovascular and respiratory issues. This study aimed to evaluate the association of hematological and lipid profile parameters with respiratory functions in Class I obese young adults. Method: This cross-sectional, multicenter study was carried out at Isra University Hospital, Memon Medical Complex, and Rajputana Hospital in Hyderabad between April 2021 and July 2024. 376 Young adults within the age bracket of 18-35 years, both males and females, were recruited in the study via a convenience sampling technique. The anthropometric measurements of participants were taken. Afterward, fasting blood samples were collected for biochemical analysis. Lipid profiles were assessed using the Micro Lab 300 machine. The data collected from respondents were entered and analyzed using MedCalc Statistical Software. The Pearson correlation test was applied to measure the strength of the association between variables. P level <0.05 was considered significant. Results: The mean age of male and female participants was 26.60±4.41 and 26.11±3.28 years, respectively. The inverse relation between lung capacity and lipid profile was observed (p<0.005), indicating reduced lung capacity with higher cholesterol. Hemoglobin also correlates negatively with VC (r = -0.32, p = 0.0003), FVC (r = -0.26, p = 0.0029), and TLC (r = -0.33, p = 0.002), suggesting increased blood viscosity may impair oxygen transport. Conclusion: The findings suggest a fair to moderate correlation between Hematological and Lipid profile parameters with respiratory functions in class I obese young adults.
ISSN:2313-7371
2308-2593