Sensitivity and Specificity of Pulse Oximetry for Congenital Heart Disease Screening in Newborn: A Meta-Analysis
Background: Early detection for Congenital Heart Disease (CHD) using pulse oximetry is a routine procedure for newborn. Pulse Oximetry Screening (POS) has been shown to be effective in detecting CHD. Aims: To evaluate the accuracy of POS through sensitivity and specificity in detecting CHD. M...
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Yayasan Aliansi Cendekiawan Indonesia Thailand
2024-11-01
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| Series: | GHMJ (Global Health Management Journal) |
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| Online Access: | https://publications.inschool.id/index.php/ghmj/article/view/1020 |
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| author | Ilma Syifannisa Raden Ayu Libert Gatho Reza Valentine Dodo Islamuddin Khomara Rangkuti |
| author_facet | Ilma Syifannisa Raden Ayu Libert Gatho Reza Valentine Dodo Islamuddin Khomara Rangkuti |
| author_sort | Ilma Syifannisa |
| collection | DOAJ |
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Background: Early detection for Congenital Heart Disease (CHD) using pulse oximetry is a routine procedure for newborn. Pulse Oximetry Screening (POS) has been shown to be effective in detecting CHD.
Aims: To evaluate the accuracy of POS through sensitivity and specificity in detecting CHD.
Methods: In this meta-analysis, we conducted a search on Pubmed, Scopus, and ScienceDirect for studies that were published up to June 20, 2024. We selected studies that assessed the sensitivity and specificity of POS for the screening of CHD in newborn babies in a hospital or home setting, regardless of gestational age at birth and excluded newborns with a previous diagnosis of CHD. We used RevMan5 software (QUADAS-2: Quality Assessment of Diagnostic Accuracy Studies-2) to assess the quality of the studies included and used Stata/SE 16.0 software to pool the sensitivity and specificity.
Results: The results showed that 17 studies, including 413,516 newborns, had pooled sensitivity and specificity of 0.69 (95% CI: 0.57-0.81) and 0.93 (95% CI: 0.85-1.00).
Conclusion: This study’s results suggest that POS has moderate sensitivity and high specificity in screening CHD in newborns. It can be concluded that there is a prospective usefulness of POS as a valuable tool in clinical practice for screening and management of CHD, especially in settings where access to higher diagnostic technologies may be limited.
Received: 25 September 2024 | Reviewed: 20 October 2024 |
Revised: 13 November 2024 | Accepted: 30 November 2024.
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| format | Article |
| id | doaj-art-8e4366341fda47f196cf52b5a7f02080 |
| institution | Kabale University |
| issn | 2580-9296 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Yayasan Aliansi Cendekiawan Indonesia Thailand |
| record_format | Article |
| series | GHMJ (Global Health Management Journal) |
| spelling | doaj-art-8e4366341fda47f196cf52b5a7f020802024-12-04T09:56:57ZengYayasan Aliansi Cendekiawan Indonesia ThailandGHMJ (Global Health Management Journal)2580-92962024-11-017410.35898/ghmj-741020Sensitivity and Specificity of Pulse Oximetry for Congenital Heart Disease Screening in Newborn: A Meta-AnalysisIlma Syifannisa0https://orcid.org/0009-0004-4590-5249Raden Ayu Libert Gatho Reza Valentine1https://orcid.org/0009-0003-9890-076XDodo Islamuddin Khomara Rangkuti2https://orcid.org/0009-0008-9029-7771Faculty of Medicine, Universitas Swadaya Gunung Jati, IndonesiaFaculty of Medicine, Universitas Swadaya Gunung Jati, IndonesiaGeneral Practitioner, Ciawi Hermina Hospital, Bogor, Jawa Barat, Indonesia Background: Early detection for Congenital Heart Disease (CHD) using pulse oximetry is a routine procedure for newborn. Pulse Oximetry Screening (POS) has been shown to be effective in detecting CHD. Aims: To evaluate the accuracy of POS through sensitivity and specificity in detecting CHD. Methods: In this meta-analysis, we conducted a search on Pubmed, Scopus, and ScienceDirect for studies that were published up to June 20, 2024. We selected studies that assessed the sensitivity and specificity of POS for the screening of CHD in newborn babies in a hospital or home setting, regardless of gestational age at birth and excluded newborns with a previous diagnosis of CHD. We used RevMan5 software (QUADAS-2: Quality Assessment of Diagnostic Accuracy Studies-2) to assess the quality of the studies included and used Stata/SE 16.0 software to pool the sensitivity and specificity. Results: The results showed that 17 studies, including 413,516 newborns, had pooled sensitivity and specificity of 0.69 (95% CI: 0.57-0.81) and 0.93 (95% CI: 0.85-1.00). Conclusion: This study’s results suggest that POS has moderate sensitivity and high specificity in screening CHD in newborns. It can be concluded that there is a prospective usefulness of POS as a valuable tool in clinical practice for screening and management of CHD, especially in settings where access to higher diagnostic technologies may be limited. Received: 25 September 2024 | Reviewed: 20 October 2024 | Revised: 13 November 2024 | Accepted: 30 November 2024. https://publications.inschool.id/index.php/ghmj/article/view/1020Congenital heart diseaseNewbornPulse oximetry |
| spellingShingle | Ilma Syifannisa Raden Ayu Libert Gatho Reza Valentine Dodo Islamuddin Khomara Rangkuti Sensitivity and Specificity of Pulse Oximetry for Congenital Heart Disease Screening in Newborn: A Meta-Analysis GHMJ (Global Health Management Journal) Congenital heart disease Newborn Pulse oximetry |
| title | Sensitivity and Specificity of Pulse Oximetry for Congenital Heart Disease Screening in Newborn: A Meta-Analysis |
| title_full | Sensitivity and Specificity of Pulse Oximetry for Congenital Heart Disease Screening in Newborn: A Meta-Analysis |
| title_fullStr | Sensitivity and Specificity of Pulse Oximetry for Congenital Heart Disease Screening in Newborn: A Meta-Analysis |
| title_full_unstemmed | Sensitivity and Specificity of Pulse Oximetry for Congenital Heart Disease Screening in Newborn: A Meta-Analysis |
| title_short | Sensitivity and Specificity of Pulse Oximetry for Congenital Heart Disease Screening in Newborn: A Meta-Analysis |
| title_sort | sensitivity and specificity of pulse oximetry for congenital heart disease screening in newborn a meta analysis |
| topic | Congenital heart disease Newborn Pulse oximetry |
| url | https://publications.inschool.id/index.php/ghmj/article/view/1020 |
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