Differential expression and functional analysis of circular RNAs and m6A modifications in children with Philadelphia chromosome-positive acute lymphoblastic leukemia

Differential expression and functional analysis of circular RNAs and m6A modifications in children with Philadelphia chromosome-positive acute lymphoblastic leukemia

Abstract Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukaemia (ALL) in childhood is associated with dismal outcomes, in large part due to challenges in diagnosis and monitoring therapeutic efficacy. Recent studies suggest that circular RNAs (circRNAs) are potential diagnostic and pro...

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Bibliographic Details
Main Authors: Lichun Xie, Ye Xu, Chuiqin Fan, Maochuan Liao, Guichi Zhou, Chen Fen, Lian Ma, Fei-Qiu Wen
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Circular RNA
Philadelphia chromosome-positive acute lymphoblastic leukaemia
N6-methyladenosine
Online Access:https://doi.org/10.1038/s41598-025-97345-0
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