Sucrose in infected wounds: a scientific basis and speculations

Sucrose use in wound treatment is a common practice that seems to promote tissue healing and reduce microbial load. The objective here was thus to analyze the scientific evidence through an integrative review to determinate indications and contraindications for use of sucrose in the form of granula...

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Bibliographic Details
Main Authors: Gabriela Oliver Rossi, Danielle Bezerra Cabral, Camila Megumi Naka Shimura, Denise de Andrade
Format: Article
Language:English
Published: Universidade Federal do Ceará 2013-10-01
Series:Rev Rene
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Online Access:https://periodicos.ufc.br/rene/article/view/3644
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Summary:Sucrose use in wound treatment is a common practice that seems to promote tissue healing and reduce microbial load. The objective here was thus to analyze the scientific evidence through an integrative review to determinate indications and contraindications for use of sucrose in the form of granulated, brown (unrefined muscovado sugar) and/or refined sugar in infected wounds and thus assist the professional in clinical decision-making. Ten studies published in full articles were selected, from the period 2002 to 2012 and indexed in the PubMed, Cinahl, Lilacs and Cochrane databases. Considering the analysis of studies, mostly experimental in the animal model, sugar’s effectiveness in tissue repair was verified, as was positive modulation in the inflammatory response. To elucidate the mechanisms or action of sucrose in the wound, further clinical trials are recommended in order to standardize the concentration, volume and frequency of sucrose in changes of wound dressings. DOI:https://doi.org/10.15253/2175-6783.20130005000020
ISSN:1517-3852
2175-6783