Bioinformatic Characterization of the Functional and Structural Effect of Single Nucleotide Mutations in Patients with High-Grade Glioma

Bioinformatic Characterization of the Functional and Structural Effect of Single Nucleotide Mutations in Patients with High-Grade Glioma

<b>Background:</b> Gliomas are neoplasms of the central nervous system that originate in glial cells. The genetic characteristics of this type of neoplasm are the loss of function of tumor suppressor genes such as <i>TP53</i> and somatic mutations in genes such as <i>ID...

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Bibliographic Details
Main Authors: Sara Vélez Gómez, Juliana María Martínez Garro, León Darío Ortiz Gómez, Jorge Emilio Salazar Flórez, Fernando P. Monroy, Ronald Guillermo Peláez Sánchez
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Biomedicines
Subjects:
neoplasia of the central nervous system
computational analysis
protein
variant
<i>TP53</i>
<i>IDH1</i>
Online Access:https://www.mdpi.com/2227-9059/12/10/2287
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