Retinal Nerve Fiber Layer Decrease during Glycemic Control in Type 2 Diabetes
Purpose. To assess an effect of glycemic control on retinal nerve fiber layer (RNFL) in type 2 diabetes mellitus. Methods. Thirty-eight eyes of 38 patients with type 2 diabetes undergoing blood glucose regulation were enrolled. All patients were examined at (1) initial visit, (2) 1 month, (3) 2 mon...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2010/569215 |
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| _version_ | 1849400600801837056 |
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| author | Masahiko Sugimoto Mikio Sasoh Masashi Ido Chisato Narushima Yukitaka Uji |
| author_facet | Masahiko Sugimoto Mikio Sasoh Masashi Ido Chisato Narushima Yukitaka Uji |
| author_sort | Masahiko Sugimoto |
| collection | DOAJ |
| description | Purpose. To assess an effect of glycemic control on retinal nerve fiber layer (RNFL) in type 2 diabetes mellitus.
Methods. Thirty-eight eyes of 38 patients with type 2 diabetes undergoing blood glucose regulation were enrolled. All patients were examined at (1) initial visit, (2) 1 month, (3) 2 months, and (4) 4-month after the initial examination. On each occasion, glycosylated hemoglobin (HbA1c) levels and optical coherence tomography (OCT) scanning for RNFL thickness were evaluated. 360 degree circular OCT scans with a diameter of 3.4 mm centered on the optic disc were performed.
Results. Significant RNFL decrease was seen in the superior area between initial and 4 months examination (𝑃=.043). The relationship between the changes in HbA1c and the changes in RNFL thickness was observed in superior, temporal, and inferior area (𝑃<.05) at 4 months. Conclusions. This study suggests that the glycemic control affects RNFL within 4 months. |
| format | Article |
| id | doaj-art-8e09b725a20f442ab0b7d147c6b65e2f |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-8e09b725a20f442ab0b7d147c6b65e2f2025-08-20T03:37:57ZengWileyJournal of Ophthalmology2090-004X2090-00582010-01-01201010.1155/2010/569215569215Retinal Nerve Fiber Layer Decrease during Glycemic Control in Type 2 DiabetesMasahiko Sugimoto0Mikio Sasoh1Masashi Ido2Chisato Narushima3Yukitaka Uji4Department of Ophthalmology, School of Medicine, Mie University, 2-174, Edobashi, Tsu, Mie 514-8507, JapanDepartment of Ophthalmology, School of Medicine, Mie University, 2-174, Edobashi, Tsu, Mie 514-8507, JapanDepartment of Ophthalmology, Yamada Red Cross Hospital, 810, Takamuku, Misono, Ise, Mie 516-0805, JapanDepartment of Ophthalmology, School of Medicine, Mie University, 2-174, Edobashi, Tsu, Mie 514-8507, JapanDepartment of Ophthalmology, School of Medicine, Mie University, 2-174, Edobashi, Tsu, Mie 514-8507, JapanPurpose. To assess an effect of glycemic control on retinal nerve fiber layer (RNFL) in type 2 diabetes mellitus. Methods. Thirty-eight eyes of 38 patients with type 2 diabetes undergoing blood glucose regulation were enrolled. All patients were examined at (1) initial visit, (2) 1 month, (3) 2 months, and (4) 4-month after the initial examination. On each occasion, glycosylated hemoglobin (HbA1c) levels and optical coherence tomography (OCT) scanning for RNFL thickness were evaluated. 360 degree circular OCT scans with a diameter of 3.4 mm centered on the optic disc were performed. Results. Significant RNFL decrease was seen in the superior area between initial and 4 months examination (𝑃=.043). The relationship between the changes in HbA1c and the changes in RNFL thickness was observed in superior, temporal, and inferior area (𝑃<.05) at 4 months. Conclusions. This study suggests that the glycemic control affects RNFL within 4 months.http://dx.doi.org/10.1155/2010/569215 |
| spellingShingle | Masahiko Sugimoto Mikio Sasoh Masashi Ido Chisato Narushima Yukitaka Uji Retinal Nerve Fiber Layer Decrease during Glycemic Control in Type 2 Diabetes Journal of Ophthalmology |
| title | Retinal Nerve Fiber Layer Decrease during Glycemic Control in Type 2 Diabetes |
| title_full | Retinal Nerve Fiber Layer Decrease during Glycemic Control in Type 2 Diabetes |
| title_fullStr | Retinal Nerve Fiber Layer Decrease during Glycemic Control in Type 2 Diabetes |
| title_full_unstemmed | Retinal Nerve Fiber Layer Decrease during Glycemic Control in Type 2 Diabetes |
| title_short | Retinal Nerve Fiber Layer Decrease during Glycemic Control in Type 2 Diabetes |
| title_sort | retinal nerve fiber layer decrease during glycemic control in type 2 diabetes |
| url | http://dx.doi.org/10.1155/2010/569215 |
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