Inflammatory Bowel Disease Patients Are Frequently Nonadherent to Scheduled Induction and Maintenance Infliximab Therapy: A Canadian Cohort Study
BACKGROUND: Adherence to maintenance medication regimens in inflammatory bowel disease patients has traditionally been poor. Although infliximab has demonstrated efficacy in inducing and maintaining disease remission, adherence to regularly scheduled infliximab infusions is required to maintain ther...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Canadian Journal of Gastroenterology and Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2015/378628 |
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| author | Christopher Ma Chad J Evaschesen Grenvil Gracias Vivian W Huang Darryl K Fedorak Karen I Kroeker Levinus A Dieleman Brendan P Halloran Richard N Fedorak |
| author_facet | Christopher Ma Chad J Evaschesen Grenvil Gracias Vivian W Huang Darryl K Fedorak Karen I Kroeker Levinus A Dieleman Brendan P Halloran Richard N Fedorak |
| author_sort | Christopher Ma |
| collection | DOAJ |
| description | BACKGROUND: Adherence to maintenance medication regimens in inflammatory bowel disease patients has traditionally been poor. Although infliximab has demonstrated efficacy in inducing and maintaining disease remission, adherence to regularly scheduled infliximab infusions is required to maintain therapeutic trough drug levels and prevent the development of anti-infliximab antibodies. |
| format | Article |
| id | doaj-art-8dfd2d200003405ead0b6d20c4c75971 |
| institution | Kabale University |
| issn | 2291-2789 2291-2797 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology and Hepatology |
| spelling | doaj-art-8dfd2d200003405ead0b6d20c4c759712025-02-03T05:45:12ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972015-01-0129630931410.1155/2015/378628Inflammatory Bowel Disease Patients Are Frequently Nonadherent to Scheduled Induction and Maintenance Infliximab Therapy: A Canadian Cohort StudyChristopher Ma0Chad J Evaschesen1Grenvil Gracias2Vivian W Huang3Darryl K Fedorak4Karen I Kroeker5Levinus A Dieleman6Brendan P Halloran7Richard N Fedorak8Division of Gastroenterology, University of Alberta, Edmonton, Alberta, CanadaDivision of Gastroenterology, University of Alberta, Edmonton, Alberta, CanadaDivision of Gastroenterology, University of Alberta, Edmonton, Alberta, CanadaDivision of Gastroenterology, University of Alberta, Edmonton, Alberta, CanadaDivision of Gastroenterology, University of Alberta, Edmonton, Alberta, CanadaDivision of Gastroenterology, University of Alberta, Edmonton, Alberta, CanadaDivision of Gastroenterology, University of Alberta, Edmonton, Alberta, CanadaDivision of Gastroenterology, University of Alberta, Edmonton, Alberta, CanadaDivision of Gastroenterology, University of Alberta, Edmonton, Alberta, CanadaBACKGROUND: Adherence to maintenance medication regimens in inflammatory bowel disease patients has traditionally been poor. Although infliximab has demonstrated efficacy in inducing and maintaining disease remission, adherence to regularly scheduled infliximab infusions is required to maintain therapeutic trough drug levels and prevent the development of anti-infliximab antibodies.http://dx.doi.org/10.1155/2015/378628 |
| spellingShingle | Christopher Ma Chad J Evaschesen Grenvil Gracias Vivian W Huang Darryl K Fedorak Karen I Kroeker Levinus A Dieleman Brendan P Halloran Richard N Fedorak Inflammatory Bowel Disease Patients Are Frequently Nonadherent to Scheduled Induction and Maintenance Infliximab Therapy: A Canadian Cohort Study Canadian Journal of Gastroenterology and Hepatology |
| title | Inflammatory Bowel Disease Patients Are Frequently Nonadherent to Scheduled Induction and Maintenance Infliximab Therapy: A Canadian Cohort Study |
| title_full | Inflammatory Bowel Disease Patients Are Frequently Nonadherent to Scheduled Induction and Maintenance Infliximab Therapy: A Canadian Cohort Study |
| title_fullStr | Inflammatory Bowel Disease Patients Are Frequently Nonadherent to Scheduled Induction and Maintenance Infliximab Therapy: A Canadian Cohort Study |
| title_full_unstemmed | Inflammatory Bowel Disease Patients Are Frequently Nonadherent to Scheduled Induction and Maintenance Infliximab Therapy: A Canadian Cohort Study |
| title_short | Inflammatory Bowel Disease Patients Are Frequently Nonadherent to Scheduled Induction and Maintenance Infliximab Therapy: A Canadian Cohort Study |
| title_sort | inflammatory bowel disease patients are frequently nonadherent to scheduled induction and maintenance infliximab therapy a canadian cohort study |
| url | http://dx.doi.org/10.1155/2015/378628 |
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