Electronic Cigarette and Atherosclerosis: A Comprehensive Literature Review of Latest Evidences

Coronary artery diseases (CAD), also known as coronary heart disease (CHD), are the world’s leading cause of death. The basis of coronary artery disease is the narrowing of the heart coronary artery lumen due to atherosclerosis. The use of electronic cigarettes has increased significantly over the y...

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Main Authors: Vito Anggarino Damay, null Setiawan, Ronny Lesmana, M. Rizki Akbar, Antonia Anna Lukito, Vita M. Tarawan, Januar W. Martha, J. Nugroho
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:International Journal of Vascular Medicine
Online Access:http://dx.doi.org/10.1155/2022/4136811
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author Vito Anggarino Damay
null Setiawan
Ronny Lesmana
M. Rizki Akbar
Antonia Anna Lukito
Vita M. Tarawan
Januar W. Martha
J. Nugroho
author_facet Vito Anggarino Damay
null Setiawan
Ronny Lesmana
M. Rizki Akbar
Antonia Anna Lukito
Vita M. Tarawan
Januar W. Martha
J. Nugroho
author_sort Vito Anggarino Damay
collection DOAJ
description Coronary artery diseases (CAD), also known as coronary heart disease (CHD), are the world’s leading cause of death. The basis of coronary artery disease is the narrowing of the heart coronary artery lumen due to atherosclerosis. The use of electronic cigarettes has increased significantly over the years. However, harmful effects of electronic cigarettes are still not firm. The aim of this article is to review the impact of electronic cigarette and its role in the pathogenesis of atherosclerosis from recent studies. The results showed that several chemical compounds, such as nicotine, propylene glycol, particulate matters, heavy metals, and flavorings, in electronic cigarette induce atherosclerosis with each molecular mechanism that lead to atherosclerosis progression by formation of ROS, endothelial dysfunction, and inflammation. Further research is still needed to determine the exact mechanism and provide more clinical evidence.
format Article
id doaj-art-8dfc135dcef04413bc63093f43fe820d
institution OA Journals
issn 2090-2832
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publishDate 2022-01-01
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record_format Article
series International Journal of Vascular Medicine
spelling doaj-art-8dfc135dcef04413bc63093f43fe820d2025-08-20T02:09:42ZengWileyInternational Journal of Vascular Medicine2090-28322022-01-01202210.1155/2022/4136811Electronic Cigarette and Atherosclerosis: A Comprehensive Literature Review of Latest EvidencesVito Anggarino Damay0null Setiawan1Ronny Lesmana2M. Rizki Akbar3Antonia Anna Lukito4Vita M. Tarawan5Januar W. Martha6J. Nugroho7Department of Cardiovascular MedicineDepartment of Biomedical SciencesDepartment of Biomedical SciencesDepartment of Cardiology and VascularDepartment of Cardiovascular MedicineDepartment of Biomedical SciencesDepartment of Cardiology and VascularDepartment of Cardiology and VascularCoronary artery diseases (CAD), also known as coronary heart disease (CHD), are the world’s leading cause of death. The basis of coronary artery disease is the narrowing of the heart coronary artery lumen due to atherosclerosis. The use of electronic cigarettes has increased significantly over the years. However, harmful effects of electronic cigarettes are still not firm. The aim of this article is to review the impact of electronic cigarette and its role in the pathogenesis of atherosclerosis from recent studies. The results showed that several chemical compounds, such as nicotine, propylene glycol, particulate matters, heavy metals, and flavorings, in electronic cigarette induce atherosclerosis with each molecular mechanism that lead to atherosclerosis progression by formation of ROS, endothelial dysfunction, and inflammation. Further research is still needed to determine the exact mechanism and provide more clinical evidence.http://dx.doi.org/10.1155/2022/4136811
spellingShingle Vito Anggarino Damay
null Setiawan
Ronny Lesmana
M. Rizki Akbar
Antonia Anna Lukito
Vita M. Tarawan
Januar W. Martha
J. Nugroho
Electronic Cigarette and Atherosclerosis: A Comprehensive Literature Review of Latest Evidences
International Journal of Vascular Medicine
title Electronic Cigarette and Atherosclerosis: A Comprehensive Literature Review of Latest Evidences
title_full Electronic Cigarette and Atherosclerosis: A Comprehensive Literature Review of Latest Evidences
title_fullStr Electronic Cigarette and Atherosclerosis: A Comprehensive Literature Review of Latest Evidences
title_full_unstemmed Electronic Cigarette and Atherosclerosis: A Comprehensive Literature Review of Latest Evidences
title_short Electronic Cigarette and Atherosclerosis: A Comprehensive Literature Review of Latest Evidences
title_sort electronic cigarette and atherosclerosis a comprehensive literature review of latest evidences
url http://dx.doi.org/10.1155/2022/4136811
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