Adipocyte-specific deletion of Dbc1 does not recapitulate healthy obesity phenotype but suggests regulation of inflammation signaling.
The protein Deleted in Breast Cancer 1 (Dbc1) is an important regulator of various transcription factors and epigenetic modulators, significantly influencing metabolism, obesity, and aging-related processes. Knockout mice lacking Dbc1 exhibit severe obesity but remain protected from liver steatosis,...
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| Main Authors: | Leonardo Santos, Rafael Sebastián Fort, Geraldine Schlapp, Karina Cal, Valentina Perez-Torrado, Maria Noel Meikle, Ana Paula Mulet, Camila Espasandín, Camila Chiesa, José R Sotelo-Silveira, Jose M Verdes, Paola Contreras, Aldo J Calliari, Martina Crispo, Jose L Badano, Carlos Escande |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0322732 |
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