Highly conductive graphene@phosphotungstic acid nanocomposite for sensitive electrochemical detection of acetaminophen based on analysis induction strategy in foods
In this work, an electrochemical sensing platform based on graphene@phosphotungstic acid nanocomposite (GR@PWA) was constructed for sensitive determination of acetaminophen (AP). The electrochemical performance of the obtained sensor (GR@PWA/GCE) was investigated by cyclic voltammetry, differential...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-03-01
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| Series: | Food Chemistry Advances |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772753X25000243 |
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| author | Ruiyu He Jingjie Zhang Shixin Li Yuzhen Yang Yaru Xu Zhixiang Xu Yufeng Sun |
| author_facet | Ruiyu He Jingjie Zhang Shixin Li Yuzhen Yang Yaru Xu Zhixiang Xu Yufeng Sun |
| author_sort | Ruiyu He |
| collection | DOAJ |
| description | In this work, an electrochemical sensing platform based on graphene@phosphotungstic acid nanocomposite (GR@PWA) was constructed for sensitive determination of acetaminophen (AP). The electrochemical performance of the obtained sensor (GR@PWA/GCE) was investigated by cyclic voltammetry, differential pulse voltammetry and electrochemical impedance spectroscopy. The calculated effective active area of GR@PWA/GCE was 2.22 times than that of bare glassy carbon electrode. Under the optimal conditions, a good linear relationship with AP concentration ranging from 1 μM to 100 μM and a lower limit of detection (0.305 μM) were obtained. The proposed sensing platform exhibited excellent anti-interference capability, repeatability, reproducibility and stability. Furthermore, the beef and lamb samples were employed to perform recovery test with a satisfactory recovery rate (88.0 %-107.6 %). The content of AP in pork and chicken samples was detected by the proposed sensor and high performance liquid chromatography. The results of the two methods were compared, and no significant difference was found (P > 0.05). This analysis strategy provides a basis for further expanding the application of electrochemical sensors in food safety detection. |
| format | Article |
| id | doaj-art-8de2075d14ab45e2916ab65d9d4865a0 |
| institution | Kabale University |
| issn | 2772-753X |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry Advances |
| spelling | doaj-art-8de2075d14ab45e2916ab65d9d4865a02025-02-07T04:48:34ZengElsevierFood Chemistry Advances2772-753X2025-03-016100908Highly conductive graphene@phosphotungstic acid nanocomposite for sensitive electrochemical detection of acetaminophen based on analysis induction strategy in foodsRuiyu He0Jingjie Zhang1Shixin Li2Yuzhen Yang3Yaru Xu4Zhixiang Xu5Yufeng Sun6Key Laboratory of Food Processing Technology and Quality Control in Shandong Province, College of Food Science and Engineering, Shandong Agricultural University, Tai'an 271018, PR ChinaKey Laboratory of Food Processing Technology and Quality Control in Shandong Province, College of Food Science and Engineering, Shandong Agricultural University, Tai'an 271018, PR ChinaKey Laboratory of Food Processing Technology and Quality Control in Shandong Province, College of Food Science and Engineering, Shandong Agricultural University, Tai'an 271018, PR ChinaKey Laboratory of Food Processing Technology and Quality Control in Shandong Province, College of Food Science and Engineering, Shandong Agricultural University, Tai'an 271018, PR ChinaKey Laboratory of Food Processing Technology and Quality Control in Shandong Province, College of Food Science and Engineering, Shandong Agricultural University, Tai'an 271018, PR ChinaKey Laboratory of Food Processing Technology and Quality Control in Shandong Province, College of Food Science and Engineering, Shandong Agricultural University, Tai'an 271018, PR ChinaCorresponding author.; Key Laboratory of Food Processing Technology and Quality Control in Shandong Province, College of Food Science and Engineering, Shandong Agricultural University, Tai'an 271018, PR ChinaIn this work, an electrochemical sensing platform based on graphene@phosphotungstic acid nanocomposite (GR@PWA) was constructed for sensitive determination of acetaminophen (AP). The electrochemical performance of the obtained sensor (GR@PWA/GCE) was investigated by cyclic voltammetry, differential pulse voltammetry and electrochemical impedance spectroscopy. The calculated effective active area of GR@PWA/GCE was 2.22 times than that of bare glassy carbon electrode. Under the optimal conditions, a good linear relationship with AP concentration ranging from 1 μM to 100 μM and a lower limit of detection (0.305 μM) were obtained. The proposed sensing platform exhibited excellent anti-interference capability, repeatability, reproducibility and stability. Furthermore, the beef and lamb samples were employed to perform recovery test with a satisfactory recovery rate (88.0 %-107.6 %). The content of AP in pork and chicken samples was detected by the proposed sensor and high performance liquid chromatography. The results of the two methods were compared, and no significant difference was found (P > 0.05). This analysis strategy provides a basis for further expanding the application of electrochemical sensors in food safety detection.http://www.sciencedirect.com/science/article/pii/S2772753X25000243Electrochemical sensorGraphene@phosphotungstic acid nanocompositeElectrocatalysisAcetaminophen |
| spellingShingle | Ruiyu He Jingjie Zhang Shixin Li Yuzhen Yang Yaru Xu Zhixiang Xu Yufeng Sun Highly conductive graphene@phosphotungstic acid nanocomposite for sensitive electrochemical detection of acetaminophen based on analysis induction strategy in foods Food Chemistry Advances Electrochemical sensor Graphene@phosphotungstic acid nanocomposite Electrocatalysis Acetaminophen |
| title | Highly conductive graphene@phosphotungstic acid nanocomposite for sensitive electrochemical detection of acetaminophen based on analysis induction strategy in foods |
| title_full | Highly conductive graphene@phosphotungstic acid nanocomposite for sensitive electrochemical detection of acetaminophen based on analysis induction strategy in foods |
| title_fullStr | Highly conductive graphene@phosphotungstic acid nanocomposite for sensitive electrochemical detection of acetaminophen based on analysis induction strategy in foods |
| title_full_unstemmed | Highly conductive graphene@phosphotungstic acid nanocomposite for sensitive electrochemical detection of acetaminophen based on analysis induction strategy in foods |
| title_short | Highly conductive graphene@phosphotungstic acid nanocomposite for sensitive electrochemical detection of acetaminophen based on analysis induction strategy in foods |
| title_sort | highly conductive graphene phosphotungstic acid nanocomposite for sensitive electrochemical detection of acetaminophen based on analysis induction strategy in foods |
| topic | Electrochemical sensor Graphene@phosphotungstic acid nanocomposite Electrocatalysis Acetaminophen |
| url | http://www.sciencedirect.com/science/article/pii/S2772753X25000243 |
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