Chronic inflammation and angiogenic signaling axis impairs differentiation of dental-pulp stem cells.

Chronic inflammation and angiogenic signaling axis impairs differentiation of dental-pulp stem cells.

Dental-pulp tissue is often exposed to inflammatory injury. Sequested growth factors or angiogenic signaling proteins that are released following inflammatory injury play a pivotal role in the formation of reparative dentin. While limited or moderate angiogenesis may be helpful for dental pulp maint...

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Bibliographic Details
Main Authors: Michael Boyle, Crystal Chun, Chelsee Strojny, Raghuvaran Narayanan, Amelia Bartholomew, Premanand Sundivakkam, Satish Alapati
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0113419&type=printable
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