Retinitis linked to human herpesvirus type 6: a case study in a splenectomised patient
Abstract Human herpesvirus-6 (HHV-6) is a member of the HHV family and is a rare cause of infectious uveitis. We report a case of a splenectomised patient, hospitalised due to invasive pneumococcal disease, who was diagnosed with retinitis in the right eye, with good visual acuity (0.1 LogMAR). Give...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2025-02-01
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| Series: | Journal of Ophthalmic Inflammation and Infection |
| Online Access: | https://doi.org/10.1186/s12348-025-00460-2 |
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| author | Joana Santos-Oliveira Ana Maria Cunha Ana Filipa Moleiro Margarida Ribeiro Sónia Torres-Costa Cláudia Oliveira-Ferreira Ana Catarina Pedrosa Joana Araújo Luís Figueira Marta Silva |
| author_facet | Joana Santos-Oliveira Ana Maria Cunha Ana Filipa Moleiro Margarida Ribeiro Sónia Torres-Costa Cláudia Oliveira-Ferreira Ana Catarina Pedrosa Joana Araújo Luís Figueira Marta Silva |
| author_sort | Joana Santos-Oliveira |
| collection | DOAJ |
| description | Abstract Human herpesvirus-6 (HHV-6) is a member of the HHV family and is a rare cause of infectious uveitis. We report a case of a splenectomised patient, hospitalised due to invasive pneumococcal disease, who was diagnosed with retinitis in the right eye, with good visual acuity (0.1 LogMAR). Given the presence of HHV-6 Polymerase chain reaction (PCR) in the cerebrospinal fluid and the serum and the coexistence of a severe central nervous system infection, the ophthalmological features were attributed to the HHV-6 infection. He was treated with topical corticosteroid eyedrops, cyclopentolate, and prednisolone acetate ointment and systemically with intravenous ganciclovir 5 mg/kg bid for 14 days and then oral valganciclovir 900 mg bid for 4 weeks. The diagnosis was promptly presumed, enabling the early initiation of appropriate treatment and contributing to the preservation of the good visual acuity initially observed. |
| format | Article |
| id | doaj-art-8dd3035343fb4f5fa5ac3280e2c9ed16 |
| institution | DOAJ |
| issn | 1869-5760 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Journal of Ophthalmic Inflammation and Infection |
| spelling | doaj-art-8dd3035343fb4f5fa5ac3280e2c9ed162025-08-20T03:01:00ZengSpringerOpenJournal of Ophthalmic Inflammation and Infection1869-57602025-02-011511610.1186/s12348-025-00460-2Retinitis linked to human herpesvirus type 6: a case study in a splenectomised patientJoana Santos-Oliveira0Ana Maria Cunha1Ana Filipa Moleiro2Margarida Ribeiro3Sónia Torres-Costa4Cláudia Oliveira-Ferreira5Ana Catarina Pedrosa6Joana Araújo7Luís Figueira8Marta Silva9Department of Ophthalmology, Centro Hospitalar Universitário de São JoãoDepartment of Ophthalmology, Centro Hospitalar Universitário de São JoãoDepartment of Ophthalmology, Centro Hospitalar Universitário de São JoãoDepartment of Ophthalmology, Centro Hospitalar Universitário de São JoãoDepartment of Ophthalmology, Centro Hospitalar Universitário de São JoãoDepartment of Ophthalmology, Centro Hospitalar Universitário de São JoãoDepartment of Ophthalmology, Centro Hospitalar Universitário de São JoãoDepartment of Ophthalmology, Centro Hospitalar Universitário de São JoãoDepartment of Ophthalmology, Centro Hospitalar Universitário de São JoãoDepartment of Ophthalmology, Centro Hospitalar Universitário de São JoãoAbstract Human herpesvirus-6 (HHV-6) is a member of the HHV family and is a rare cause of infectious uveitis. We report a case of a splenectomised patient, hospitalised due to invasive pneumococcal disease, who was diagnosed with retinitis in the right eye, with good visual acuity (0.1 LogMAR). Given the presence of HHV-6 Polymerase chain reaction (PCR) in the cerebrospinal fluid and the serum and the coexistence of a severe central nervous system infection, the ophthalmological features were attributed to the HHV-6 infection. He was treated with topical corticosteroid eyedrops, cyclopentolate, and prednisolone acetate ointment and systemically with intravenous ganciclovir 5 mg/kg bid for 14 days and then oral valganciclovir 900 mg bid for 4 weeks. The diagnosis was promptly presumed, enabling the early initiation of appropriate treatment and contributing to the preservation of the good visual acuity initially observed.https://doi.org/10.1186/s12348-025-00460-2 |
| spellingShingle | Joana Santos-Oliveira Ana Maria Cunha Ana Filipa Moleiro Margarida Ribeiro Sónia Torres-Costa Cláudia Oliveira-Ferreira Ana Catarina Pedrosa Joana Araújo Luís Figueira Marta Silva Retinitis linked to human herpesvirus type 6: a case study in a splenectomised patient Journal of Ophthalmic Inflammation and Infection |
| title | Retinitis linked to human herpesvirus type 6: a case study in a splenectomised patient |
| title_full | Retinitis linked to human herpesvirus type 6: a case study in a splenectomised patient |
| title_fullStr | Retinitis linked to human herpesvirus type 6: a case study in a splenectomised patient |
| title_full_unstemmed | Retinitis linked to human herpesvirus type 6: a case study in a splenectomised patient |
| title_short | Retinitis linked to human herpesvirus type 6: a case study in a splenectomised patient |
| title_sort | retinitis linked to human herpesvirus type 6 a case study in a splenectomised patient |
| url | https://doi.org/10.1186/s12348-025-00460-2 |
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