Corneal stromal mapping characteristics in normal corneas using anterior segment SD-OCT
This study investigated how normal corneal stromal profiles change with age, sex, and corrected intraocular pressure (IOP). A retrospective observational analytical study was conducted in Jordan, employing anterior segment spectral-domain optical coherence tomography AS-OCT, a measured corneal strom...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-12-01
|
| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2024.1485718/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850106101137145856 |
|---|---|
| author | Mohammad Abusamak Mohammad Abusamak Sara Mazen Issa Amal F. Alomari Husam A. Alsalamat Husam A. Alsalamat Nour S. Haj Ali Abdallah Izmegna Mais Shawashreh Mahmoud Abu Samak Talal M. Abusamak Talal M. Abusamak |
| author_facet | Mohammad Abusamak Mohammad Abusamak Sara Mazen Issa Amal F. Alomari Husam A. Alsalamat Husam A. Alsalamat Nour S. Haj Ali Abdallah Izmegna Mais Shawashreh Mahmoud Abu Samak Talal M. Abusamak Talal M. Abusamak |
| author_sort | Mohammad Abusamak |
| collection | DOAJ |
| description | This study investigated how normal corneal stromal profiles change with age, sex, and corrected intraocular pressure (IOP). A retrospective observational analytical study was conducted in Jordan, employing anterior segment spectral-domain optical coherence tomography AS-OCT, a measured corneal stromal thickness (CST) in 134 eyes across the central 6-mm corneal diameter. People between the ages of 18 and 79 were included, and the mean CST values were linked to age groups, IOP, and cis-gender populations, with the exclusion of certain eye conditions. The central stroma was thinnest at 484.6 (±32.6) μm, contrasting with the outer peripheral superior zone’s maximum thickness at 549.3 (±40.6) μm. A positive correlation between CST and the 30–49 age group was noted. In conclusion, this study highlights a centrifugal CST distribution, with the central stroma being the thinnest and the superior stroma being the thickest. AS SD-OCT, employing novel algorithms, proves vital in refractive surgery planning and corneal disease diagnosis. The research offers valuable insights into age, gender, and IOP interactions with corneal stromal characteristics, enhancing clinical strategies for corneal pathologies in the Jordanian population. |
| format | Article |
| id | doaj-art-8dd156157c6e414f8a53230dd2522b7c |
| institution | OA Journals |
| issn | 2296-858X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-8dd156157c6e414f8a53230dd2522b7c2025-08-20T02:38:55ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2024-12-011110.3389/fmed.2024.14857181485718Corneal stromal mapping characteristics in normal corneas using anterior segment SD-OCTMohammad Abusamak0Mohammad Abusamak1Sara Mazen Issa2Amal F. Alomari3Husam A. Alsalamat4Husam A. Alsalamat5Nour S. Haj Ali6Abdallah Izmegna7Mais Shawashreh8Mahmoud Abu Samak9Talal M. Abusamak10Talal M. Abusamak11Department of Special Surgery, School of Medicine, Al-Balqa Applied University, Al-Salt, JordanAmman Eye Clinic, Amman, JordanDepartment of Special Surgery, School of Medicine, Al-Balqa Applied University, Al-Salt, JordanDepartment of Special Surgery, School of Medicine, Al-Balqa Applied University, Al-Salt, JordanDepartment of Special Surgery, School of Medicine, Al-Balqa Applied University, Al-Salt, JordanDepartment of Biopharmaceutics and Clinical Pharmacy, School of Pharmacy, The University of Jordan, Amman, JordanDepartment of Special Surgery, School of Medicine, Al-Balqa Applied University, Al-Salt, JordanDepartment of Special Surgery, School of Medicine, Al-Balqa Applied University, Al-Salt, JordanDepartment of Special Surgery, School of Medicine, Al-Balqa Applied University, Al-Salt, JordanDepartment of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman, JordanDepartment of Biopharmaceutics and Clinical Pharmacy, School of Pharmacy, The University of Jordan, Amman, JordanKasralainy Faculty of Medicine, Cairo University, Cairo, EgyptThis study investigated how normal corneal stromal profiles change with age, sex, and corrected intraocular pressure (IOP). A retrospective observational analytical study was conducted in Jordan, employing anterior segment spectral-domain optical coherence tomography AS-OCT, a measured corneal stromal thickness (CST) in 134 eyes across the central 6-mm corneal diameter. People between the ages of 18 and 79 were included, and the mean CST values were linked to age groups, IOP, and cis-gender populations, with the exclusion of certain eye conditions. The central stroma was thinnest at 484.6 (±32.6) μm, contrasting with the outer peripheral superior zone’s maximum thickness at 549.3 (±40.6) μm. A positive correlation between CST and the 30–49 age group was noted. In conclusion, this study highlights a centrifugal CST distribution, with the central stroma being the thinnest and the superior stroma being the thickest. AS SD-OCT, employing novel algorithms, proves vital in refractive surgery planning and corneal disease diagnosis. The research offers valuable insights into age, gender, and IOP interactions with corneal stromal characteristics, enhancing clinical strategies for corneal pathologies in the Jordanian population.https://www.frontiersin.org/articles/10.3389/fmed.2024.1485718/fullstromaophthalmologyoptical coherence tomographymappinganterior segment |
| spellingShingle | Mohammad Abusamak Mohammad Abusamak Sara Mazen Issa Amal F. Alomari Husam A. Alsalamat Husam A. Alsalamat Nour S. Haj Ali Abdallah Izmegna Mais Shawashreh Mahmoud Abu Samak Talal M. Abusamak Talal M. Abusamak Corneal stromal mapping characteristics in normal corneas using anterior segment SD-OCT Frontiers in Medicine stroma ophthalmology optical coherence tomography mapping anterior segment |
| title | Corneal stromal mapping characteristics in normal corneas using anterior segment SD-OCT |
| title_full | Corneal stromal mapping characteristics in normal corneas using anterior segment SD-OCT |
| title_fullStr | Corneal stromal mapping characteristics in normal corneas using anterior segment SD-OCT |
| title_full_unstemmed | Corneal stromal mapping characteristics in normal corneas using anterior segment SD-OCT |
| title_short | Corneal stromal mapping characteristics in normal corneas using anterior segment SD-OCT |
| title_sort | corneal stromal mapping characteristics in normal corneas using anterior segment sd oct |
| topic | stroma ophthalmology optical coherence tomography mapping anterior segment |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2024.1485718/full |
| work_keys_str_mv | AT mohammadabusamak cornealstromalmappingcharacteristicsinnormalcorneasusinganteriorsegmentsdoct AT mohammadabusamak cornealstromalmappingcharacteristicsinnormalcorneasusinganteriorsegmentsdoct AT saramazenissa cornealstromalmappingcharacteristicsinnormalcorneasusinganteriorsegmentsdoct AT amalfalomari cornealstromalmappingcharacteristicsinnormalcorneasusinganteriorsegmentsdoct AT husamaalsalamat cornealstromalmappingcharacteristicsinnormalcorneasusinganteriorsegmentsdoct AT husamaalsalamat cornealstromalmappingcharacteristicsinnormalcorneasusinganteriorsegmentsdoct AT nourshajali cornealstromalmappingcharacteristicsinnormalcorneasusinganteriorsegmentsdoct AT abdallahizmegna cornealstromalmappingcharacteristicsinnormalcorneasusinganteriorsegmentsdoct AT maisshawashreh cornealstromalmappingcharacteristicsinnormalcorneasusinganteriorsegmentsdoct AT mahmoudabusamak cornealstromalmappingcharacteristicsinnormalcorneasusinganteriorsegmentsdoct AT talalmabusamak cornealstromalmappingcharacteristicsinnormalcorneasusinganteriorsegmentsdoct AT talalmabusamak cornealstromalmappingcharacteristicsinnormalcorneasusinganteriorsegmentsdoct |