Rapid recovery in degenerative cervical myelopathy: A case report highlighting neuroplasticity following surgical decompression

Introduction: Degenerative cervical myelopathy (DCM) causes progressive compression of the spinal cord, leading to permanent and sometimes irreversible nerve damage if left untreated or not promptly treated. The nerve damage is associated with impaired sensory and motor function below the spinal cor...

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Main Authors: Wilson David Campos Figueredo, Raul Ramirez Grueso, Maria Paola Barrero Medina, Paula Andrea Arenas, José Corredor Santos, Luisa Jaimes
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Interdisciplinary Neurosurgery
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214751925000258
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author Wilson David Campos Figueredo
Raul Ramirez Grueso
Maria Paola Barrero Medina
Paula Andrea Arenas
José Corredor Santos
Luisa Jaimes
author_facet Wilson David Campos Figueredo
Raul Ramirez Grueso
Maria Paola Barrero Medina
Paula Andrea Arenas
José Corredor Santos
Luisa Jaimes
author_sort Wilson David Campos Figueredo
collection DOAJ
description Introduction: Degenerative cervical myelopathy (DCM) causes progressive compression of the spinal cord, leading to permanent and sometimes irreversible nerve damage if left untreated or not promptly treated. The nerve damage is associated with impaired sensory and motor function below the spinal cord injury (SCI) level, leading to a functional disability that affects the patient and the patient’s family quality of life. Early surgical decompression of the spinal canal remains one of the preferred options among physicians. Neuronal plasticity (NP) can take place after the initial injury and has been shown to be a complex process where the neurons use different adaptive strategies to regain their functions. Case report: In this article, we present a case of a 65-year-old male with a history of obesity and rheumatologic disease, who, without prior medical monitoring, presented with posterior cervical pain, right-sided hemicranial headache, and progressive right hemiparesis that advanced to severe quadriparesis. Magnetic resonance imaging (MRI) and computed tomography (CT) revealed a narrowed cervical canal with evidence of compressive myelopathy. During the second surgical intervention, Intraoperative Neurophysiological Monitoring (IONM) was performed, showing Motor Evoked Potentials (MEP) in the right hemibody following decompression. The patient experienced an early and successful recovery, regaining sensory and motor functions sooner than expected after the second decompression. Conclusion: Spinal cord injury (SCI) in adults is believed to cause definitive and non-treatable damage to the neurons. However, the presence of early MEP during the IONM and the rapid recovery of the patient after the surgical decompression demonstrated the potential for neuroplasticity and the opportunity to enhance it with different therapy strategies.
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spelling doaj-art-8dcee2be727648b3a5bbca0bf7ee8f3c2025-08-20T02:10:23ZengElsevierInterdisciplinary Neurosurgery2214-75192025-06-014010201310.1016/j.inat.2025.102013Rapid recovery in degenerative cervical myelopathy: A case report highlighting neuroplasticity following surgical decompressionWilson David Campos Figueredo0Raul Ramirez Grueso1Maria Paola Barrero Medina2Paula Andrea Arenas3José Corredor Santos4Luisa Jaimes5El Bosque University, Department of Neurosurgery, Los Cobos Medical Center, Bogotá, Colombia; Corresponding author at: Department of Neurosurgery, Los Cobos Medical Center, Bogota D.C, Colombia.Neurosurgeon, National University of Colombia, Department of Neurosurgery, Los Cobos Medical Center, Bogotá, ColombiaResident Physical Medicine and Rehabilitation El Bosque University, Los Cobos Medical Center. Bogotá, ColombiaPhysiatrist, El Bosque University, Department of Physical Medicine and Rehabilitation, Los Cobos Medical Center, Bogotá, ColombiaOrthopedics, Spine Surgery at the Faculty of Medical Sciences of Santa Casa de São Paulo (São Paulo - Brazil), Department of Neurosurgery, Los Cobos Medical Center, Bogotá, ColombiaNeuroradiologist, Department of Radiology and Diagnostic Imaging, Los Cobos Medical Center, Bogotá, ColombiaIntroduction: Degenerative cervical myelopathy (DCM) causes progressive compression of the spinal cord, leading to permanent and sometimes irreversible nerve damage if left untreated or not promptly treated. The nerve damage is associated with impaired sensory and motor function below the spinal cord injury (SCI) level, leading to a functional disability that affects the patient and the patient’s family quality of life. Early surgical decompression of the spinal canal remains one of the preferred options among physicians. Neuronal plasticity (NP) can take place after the initial injury and has been shown to be a complex process where the neurons use different adaptive strategies to regain their functions. Case report: In this article, we present a case of a 65-year-old male with a history of obesity and rheumatologic disease, who, without prior medical monitoring, presented with posterior cervical pain, right-sided hemicranial headache, and progressive right hemiparesis that advanced to severe quadriparesis. Magnetic resonance imaging (MRI) and computed tomography (CT) revealed a narrowed cervical canal with evidence of compressive myelopathy. During the second surgical intervention, Intraoperative Neurophysiological Monitoring (IONM) was performed, showing Motor Evoked Potentials (MEP) in the right hemibody following decompression. The patient experienced an early and successful recovery, regaining sensory and motor functions sooner than expected after the second decompression. Conclusion: Spinal cord injury (SCI) in adults is believed to cause definitive and non-treatable damage to the neurons. However, the presence of early MEP during the IONM and the rapid recovery of the patient after the surgical decompression demonstrated the potential for neuroplasticity and the opportunity to enhance it with different therapy strategies.http://www.sciencedirect.com/science/article/pii/S2214751925000258NeuroplasticitySpinal cord compressionNerve regenerationRehabilitation
spellingShingle Wilson David Campos Figueredo
Raul Ramirez Grueso
Maria Paola Barrero Medina
Paula Andrea Arenas
José Corredor Santos
Luisa Jaimes
Rapid recovery in degenerative cervical myelopathy: A case report highlighting neuroplasticity following surgical decompression
Interdisciplinary Neurosurgery
Neuroplasticity
Spinal cord compression
Nerve regeneration
Rehabilitation
title Rapid recovery in degenerative cervical myelopathy: A case report highlighting neuroplasticity following surgical decompression
title_full Rapid recovery in degenerative cervical myelopathy: A case report highlighting neuroplasticity following surgical decompression
title_fullStr Rapid recovery in degenerative cervical myelopathy: A case report highlighting neuroplasticity following surgical decompression
title_full_unstemmed Rapid recovery in degenerative cervical myelopathy: A case report highlighting neuroplasticity following surgical decompression
title_short Rapid recovery in degenerative cervical myelopathy: A case report highlighting neuroplasticity following surgical decompression
title_sort rapid recovery in degenerative cervical myelopathy a case report highlighting neuroplasticity following surgical decompression
topic Neuroplasticity
Spinal cord compression
Nerve regeneration
Rehabilitation
url http://www.sciencedirect.com/science/article/pii/S2214751925000258
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