Deletion of the Human Cytomegalovirus US2 to US11 Gene Family Members Impairs the Type-I Interferon Response

Deletion of the Human Cytomegalovirus US2 to US11 Gene Family Members Impairs the Type-I Interferon Response

Infection of cells with the human cytomegalovirus (HCMV) triggers the expression of interferon-stimulated genes (ISGs). ISGs encode proteins with antiviral functions, such as inhibiting viral replication, promoting cell death of infected cells and enhancing immune responses. HCMV has evolved mechani...

Full description

Saved in:
Bibliographic Details
Main Authors: Inessa Penner, Nadine Krämer, Julia Hirsch, Nicole Büscher, Hanno Schmidt, Bodo Plachter
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Viruses
Subjects:
cytomegalovirus
immune evasion
interferon
interferon stimulated genes
Online Access:https://www.mdpi.com/1999-4915/17/3/426
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items