MYB regulation of GST/GT mediates red petal spot development in cotton

Red petal spots are beneficial for attracting cotton pollinators and producing hybrid seeds, and the anthocyanin pathway is generally regarded as a metabolic cause of petal coloration. The current study identified an MYB-encoding gene (Gar07G09390, GaMYB) as a candidate gene involved in cotton color...

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Main Authors: Sujun Zhang, Jie Chen, Tao Jiang, Haitao Wang, Xiao Cai, Cunjing Liu, Liyuan Tang, Xinghe Li, Yaqian Sun, Jianhong Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-06-01
Series:Crop Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214514125000972
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author Sujun Zhang
Jie Chen
Tao Jiang
Haitao Wang
Xiao Cai
Cunjing Liu
Liyuan Tang
Xinghe Li
Yaqian Sun
Jianhong Zhang
author_facet Sujun Zhang
Jie Chen
Tao Jiang
Haitao Wang
Xiao Cai
Cunjing Liu
Liyuan Tang
Xinghe Li
Yaqian Sun
Jianhong Zhang
author_sort Sujun Zhang
collection DOAJ
description Red petal spots are beneficial for attracting cotton pollinators and producing hybrid seeds, and the anthocyanin pathway is generally regarded as a metabolic cause of petal coloration. The current study identified an MYB-encoding gene (Gar07G09390, GaMYB) as a candidate gene involved in cotton coloration by map-based cloning, and this MYB could positively regulate a candidate glutathione S‑transferase gene (Gar07G08900, GaGST). To unveil potentially involved genes within the GaMYB-regulating-GaGST route, color metabolites of both GaMYB- and GaGST-virus-induced gene silencing (VIGS) petals were investigated, revealing that they were largely glycosyl-decorated flavonoids. Accordingly, a transcriptomic survey of both VIGS petals identified a glycosyl-transferase gene (GaGT, Gar02G15390). Notably, this GaGT is adjacent to one of the genome-wide association study loci concerning petal spots in Gossypium arboreum, and it is also positively regulated by GaMYB. This new regulatory route including both GST and GT regulated by MYB is conserved among the three cotton species examined in this study (Gossypium arboreum, Gossypium hirsutum, and Gossypium barbadense). Accordingly, comprehensively evaluating the influence of these candidates and their homologs on cotton coloration may provide a more in-depth understanding of cotton coloration, ultimately facilitating the breeding of more colorful cotton.
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publishDate 2025-06-01
publisher KeAi Communications Co., Ltd.
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spelling doaj-art-8dc6ec45ce464301a1c7a7cd7f54a70f2025-08-20T02:37:17ZengKeAi Communications Co., Ltd.Crop Journal2214-51412025-06-0113385085910.1016/j.cj.2025.03.015MYB regulation of GST/GT mediates red petal spot development in cottonSujun Zhang0Jie Chen1Tao Jiang2Haitao Wang3Xiao Cai4Cunjing Liu5Liyuan Tang6Xinghe Li7Yaqian Sun8Jianhong Zhang9Institute of Cotton, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory Biology and Genetic Improvement of Cotton in Huanghuaihai Semiarid Area, Shijiazhuang 050051, Hebei, ChinaYazhouwan National Laboratory, Sanya 572024, Hainan, ChinaInstitute of Cash Crops, Hebei Academy of Agriculture and Forestry Sciences, Shijiazhuang 050051, Hebei, ChinaInstitute of Cotton, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory Biology and Genetic Improvement of Cotton in Huanghuaihai Semiarid Area, Shijiazhuang 050051, Hebei, ChinaInstitute of Cotton, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory Biology and Genetic Improvement of Cotton in Huanghuaihai Semiarid Area, Shijiazhuang 050051, Hebei, ChinaInstitute of Cotton, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory Biology and Genetic Improvement of Cotton in Huanghuaihai Semiarid Area, Shijiazhuang 050051, Hebei, ChinaInstitute of Cotton, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory Biology and Genetic Improvement of Cotton in Huanghuaihai Semiarid Area, Shijiazhuang 050051, Hebei, ChinaInstitute of Cotton, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory Biology and Genetic Improvement of Cotton in Huanghuaihai Semiarid Area, Shijiazhuang 050051, Hebei, ChinaInstitute of Cash Crops, Hebei Academy of Agriculture and Forestry Sciences, Shijiazhuang 050051, Hebei, ChinaInstitute of Cotton, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory Biology and Genetic Improvement of Cotton in Huanghuaihai Semiarid Area, Shijiazhuang 050051, Hebei, China; Corresponding author.Red petal spots are beneficial for attracting cotton pollinators and producing hybrid seeds, and the anthocyanin pathway is generally regarded as a metabolic cause of petal coloration. The current study identified an MYB-encoding gene (Gar07G09390, GaMYB) as a candidate gene involved in cotton coloration by map-based cloning, and this MYB could positively regulate a candidate glutathione S‑transferase gene (Gar07G08900, GaGST). To unveil potentially involved genes within the GaMYB-regulating-GaGST route, color metabolites of both GaMYB- and GaGST-virus-induced gene silencing (VIGS) petals were investigated, revealing that they were largely glycosyl-decorated flavonoids. Accordingly, a transcriptomic survey of both VIGS petals identified a glycosyl-transferase gene (GaGT, Gar02G15390). Notably, this GaGT is adjacent to one of the genome-wide association study loci concerning petal spots in Gossypium arboreum, and it is also positively regulated by GaMYB. This new regulatory route including both GST and GT regulated by MYB is conserved among the three cotton species examined in this study (Gossypium arboreum, Gossypium hirsutum, and Gossypium barbadense). Accordingly, comprehensively evaluating the influence of these candidates and their homologs on cotton coloration may provide a more in-depth understanding of cotton coloration, ultimately facilitating the breeding of more colorful cotton.http://www.sciencedirect.com/science/article/pii/S2214514125000972CottonRed-spot-petalMYB-encoding geneGlutathione S‑transferase geneGlycosyl-transferase gene
spellingShingle Sujun Zhang
Jie Chen
Tao Jiang
Haitao Wang
Xiao Cai
Cunjing Liu
Liyuan Tang
Xinghe Li
Yaqian Sun
Jianhong Zhang
MYB regulation of GST/GT mediates red petal spot development in cotton
Crop Journal
Cotton
Red-spot-petal
MYB-encoding gene
Glutathione S‑transferase gene
Glycosyl-transferase gene
title MYB regulation of GST/GT mediates red petal spot development in cotton
title_full MYB regulation of GST/GT mediates red petal spot development in cotton
title_fullStr MYB regulation of GST/GT mediates red petal spot development in cotton
title_full_unstemmed MYB regulation of GST/GT mediates red petal spot development in cotton
title_short MYB regulation of GST/GT mediates red petal spot development in cotton
title_sort myb regulation of gst gt mediates red petal spot development in cotton
topic Cotton
Red-spot-petal
MYB-encoding gene
Glutathione S‑transferase gene
Glycosyl-transferase gene
url http://www.sciencedirect.com/science/article/pii/S2214514125000972
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