The Efficacy of Tumor Characterization for Colorectal Lesions with Blue Light Imaging of a Compact Light-Emitting Diode Endoscopic System Compared to a Laser Endoscopic System: A Pilot Study
Background: A compact and cost-effective light source-processor combined 3-color light-emitting diode (LED) endoscopic system (ELUXEO-Lite: EP-6000, Fujifilm Co., Tokyo) with a magnified colonoscope (EC-6600ZP, Fujifilm Co.) has been released. Aims: In this study, we analyzed the efficacy of this sy...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2022/9998280 |
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| author | Ken Inoue Naohisa Yoshida Reo Kobayashi Yuri Tomita Hikaru Hashimoto Satoshi Sugino Ryohei Hirose Osamu Dohi Hiroaki Yasuda Ritsu Yasuda Takaaki Murakami Yutaka Inada Yoshito Itoh |
| author_facet | Ken Inoue Naohisa Yoshida Reo Kobayashi Yuri Tomita Hikaru Hashimoto Satoshi Sugino Ryohei Hirose Osamu Dohi Hiroaki Yasuda Ritsu Yasuda Takaaki Murakami Yutaka Inada Yoshito Itoh |
| author_sort | Ken Inoue |
| collection | DOAJ |
| description | Background: A compact and cost-effective light source-processor combined 3-color light-emitting diode (LED) endoscopic system (ELUXEO-Lite: EP-6000, Fujifilm Co., Tokyo) with a magnified colonoscope (EC-6600ZP, Fujifilm Co.) has been released. Aims: In this study, we analyzed the efficacy of this system for colorectal tumor characterization with magnified blue light imaging (BLI-LED) and image’s subjective and objective evaluations, compared to a magnified blue laser imaging (BLI-LASER) using a standard LASER endoscopic system. Methods: We retrospectively reviewed 37 lesions observed with both BLI-LED and BLI-LASER systems from 2019 using the Japanese narrow band imaging classification. Two representative magnified images, one BLI-LED and one BLI-LASER, of the same area of a lesion were evaluated for diagnostic accuracy and visualization quality by three experts and three non-experts. Their color difference values (CDVs) and brightness values (BVs) were also calculated as objective indicators. Results: Among 37 lesions, mean tumor size was 18.9±13.1 mm, and 21 lesions were nonpolypoid. Histopathology revealed 14 sessile serrated lesions, 7 adenomas, 12 high-grade dysplasias and T1a cancers, and 4 T1b cancers. The diagnostic accuracy rates of BLI-LED/BLI-LASER of experts and non-experts were 90.1% and 87.4% (p=0.52) and 89.2% and 89.2% (p=0.99). The percentages of instances where BLI-LED images were better, the two imaging types were equivalent, or BLI-LASER images were better were 16%/83%/1% for experts and 19%/58%/23% for non-experts (p<0.001). CDVs and BVs between BLI-LED and BLI-LASER were not significantly different (CDVs: p=0.653, BVs: p=0.518). Conclusions: BLI-LED using the compact system was noninferior to BLI-LASER for colorectal tumor characterization and image quality. |
| format | Article |
| id | doaj-art-8dc69d13eedf44b1af3acae392db268a |
| institution | Kabale University |
| issn | 1687-630X |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-8dc69d13eedf44b1af3acae392db268a2025-08-20T03:37:56ZengWileyGastroenterology Research and Practice1687-630X2022-01-01202210.1155/2022/9998280The Efficacy of Tumor Characterization for Colorectal Lesions with Blue Light Imaging of a Compact Light-Emitting Diode Endoscopic System Compared to a Laser Endoscopic System: A Pilot StudyKen Inoue0Naohisa Yoshida1Reo Kobayashi2Yuri Tomita3Hikaru Hashimoto4Satoshi Sugino5Ryohei Hirose6Osamu Dohi7Hiroaki Yasuda8Ritsu Yasuda9Takaaki Murakami10Yutaka Inada11Yoshito Itoh12Molecular Gastroenterology and HepatologyMolecular Gastroenterology and HepatologyMolecular Gastroenterology and HepatologyMolecular Gastroenterology and HepatologyMolecular Gastroenterology and HepatologyMolecular Gastroenterology and HepatologyMolecular Gastroenterology and HepatologyMolecular Gastroenterology and HepatologyMolecular Gastroenterology and HepatologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of Gastroenterology and HepatologyMolecular Gastroenterology and HepatologyBackground: A compact and cost-effective light source-processor combined 3-color light-emitting diode (LED) endoscopic system (ELUXEO-Lite: EP-6000, Fujifilm Co., Tokyo) with a magnified colonoscope (EC-6600ZP, Fujifilm Co.) has been released. Aims: In this study, we analyzed the efficacy of this system for colorectal tumor characterization with magnified blue light imaging (BLI-LED) and image’s subjective and objective evaluations, compared to a magnified blue laser imaging (BLI-LASER) using a standard LASER endoscopic system. Methods: We retrospectively reviewed 37 lesions observed with both BLI-LED and BLI-LASER systems from 2019 using the Japanese narrow band imaging classification. Two representative magnified images, one BLI-LED and one BLI-LASER, of the same area of a lesion were evaluated for diagnostic accuracy and visualization quality by three experts and three non-experts. Their color difference values (CDVs) and brightness values (BVs) were also calculated as objective indicators. Results: Among 37 lesions, mean tumor size was 18.9±13.1 mm, and 21 lesions were nonpolypoid. Histopathology revealed 14 sessile serrated lesions, 7 adenomas, 12 high-grade dysplasias and T1a cancers, and 4 T1b cancers. The diagnostic accuracy rates of BLI-LED/BLI-LASER of experts and non-experts were 90.1% and 87.4% (p=0.52) and 89.2% and 89.2% (p=0.99). The percentages of instances where BLI-LED images were better, the two imaging types were equivalent, or BLI-LASER images were better were 16%/83%/1% for experts and 19%/58%/23% for non-experts (p<0.001). CDVs and BVs between BLI-LED and BLI-LASER were not significantly different (CDVs: p=0.653, BVs: p=0.518). Conclusions: BLI-LED using the compact system was noninferior to BLI-LASER for colorectal tumor characterization and image quality.http://dx.doi.org/10.1155/2022/9998280 |
| spellingShingle | Ken Inoue Naohisa Yoshida Reo Kobayashi Yuri Tomita Hikaru Hashimoto Satoshi Sugino Ryohei Hirose Osamu Dohi Hiroaki Yasuda Ritsu Yasuda Takaaki Murakami Yutaka Inada Yoshito Itoh The Efficacy of Tumor Characterization for Colorectal Lesions with Blue Light Imaging of a Compact Light-Emitting Diode Endoscopic System Compared to a Laser Endoscopic System: A Pilot Study Gastroenterology Research and Practice |
| title | The Efficacy of Tumor Characterization for Colorectal Lesions with Blue Light Imaging of a Compact Light-Emitting Diode Endoscopic System Compared to a Laser Endoscopic System: A Pilot Study |
| title_full | The Efficacy of Tumor Characterization for Colorectal Lesions with Blue Light Imaging of a Compact Light-Emitting Diode Endoscopic System Compared to a Laser Endoscopic System: A Pilot Study |
| title_fullStr | The Efficacy of Tumor Characterization for Colorectal Lesions with Blue Light Imaging of a Compact Light-Emitting Diode Endoscopic System Compared to a Laser Endoscopic System: A Pilot Study |
| title_full_unstemmed | The Efficacy of Tumor Characterization for Colorectal Lesions with Blue Light Imaging of a Compact Light-Emitting Diode Endoscopic System Compared to a Laser Endoscopic System: A Pilot Study |
| title_short | The Efficacy of Tumor Characterization for Colorectal Lesions with Blue Light Imaging of a Compact Light-Emitting Diode Endoscopic System Compared to a Laser Endoscopic System: A Pilot Study |
| title_sort | efficacy of tumor characterization for colorectal lesions with blue light imaging of a compact light emitting diode endoscopic system compared to a laser endoscopic system a pilot study |
| url | http://dx.doi.org/10.1155/2022/9998280 |
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