Clinical analysis on risk factors and prognosis of early post-traumatic epilepsy
ABSTRACT Objective To analyze the risk factors and prognosis related to early post-traumatic epilepsy (EPTE). Methods One hundred and eighty-six patients with traumatic brain injury were enrolled. Their full clinical data were collected. Single factor analysis and logistic regression analysis of...
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| Series: | Arquivos de Neuro-Psiquiatria |
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| author | Zaiming LIU Qianxue CHEN Zhibiao CHEN Junmin WANG Daofeng TIAN Long WANG Baohui LIU Shenqi ZHANG |
| author_facet | Zaiming LIU Qianxue CHEN Zhibiao CHEN Junmin WANG Daofeng TIAN Long WANG Baohui LIU Shenqi ZHANG |
| author_sort | Zaiming LIU |
| collection | DOAJ |
| description | ABSTRACT Objective To analyze the risk factors and prognosis related to early post-traumatic epilepsy (EPTE). Methods One hundred and eighty-six patients with traumatic brain injury were enrolled. Their full clinical data were collected. Single factor analysis and logistic regression analysis of risk factors related to EPTE were performed. The prognosis of patients was determined. Results Single factor analysis showed that there were significant differences of age (p = 0.011), epilepsy history (p < 0.001), injury site (p = 0.004), injury type (p < 0.001) and injury degree (p < 0.001) between the EPTE group (40 patients) and non-EPTE group (146 patients). Logistic regression analysis showed that the injury site, injury type and injury degree were the main risk factors for EPTE. The odds ratio values of injury site, injury type and injury degree were 1.977 (1.473–2.679), 2.096 (1.543–2.842) and 2.376 (1.864–3.609), respectively. The logistic regression equation was P = Exp (-1.473 + 0.698 × injury site + 0.717 × injury type + 0.935 × injury degree). The sensitivity and specificity of injury site, injury type and injury degree for predicting EPTE were 79.2% and 80.5%, 78.9% and 85.7% and 84.2% and 81.0%, respectively. The analysis of prognosis showed that the Glasgow Outcome Scale/Activity of Daily Living Scale scores in the EPTE group were significantly lower than those in non-EPTE group (p < 0.05). Conclusions Injury site, injury type and injury degree are the main risk factors for EPTE. The prognosis of patients with traumatic brain injury can be affected by EPTE. |
| format | Article |
| id | doaj-art-8dbb1dcdad014e89990fc34bb19f27a2 |
| institution | Kabale University |
| issn | 1678-4227 |
| language | English |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-8dbb1dcdad014e89990fc34bb19f27a22025-08-20T03:37:54ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-422777637538010.1590/0004-282x20190071S0004-282X2019000600375Clinical analysis on risk factors and prognosis of early post-traumatic epilepsyZaiming LIUQianxue CHENZhibiao CHENJunmin WANGDaofeng TIANLong WANGBaohui LIUShenqi ZHANGABSTRACT Objective To analyze the risk factors and prognosis related to early post-traumatic epilepsy (EPTE). Methods One hundred and eighty-six patients with traumatic brain injury were enrolled. Their full clinical data were collected. Single factor analysis and logistic regression analysis of risk factors related to EPTE were performed. The prognosis of patients was determined. Results Single factor analysis showed that there were significant differences of age (p = 0.011), epilepsy history (p < 0.001), injury site (p = 0.004), injury type (p < 0.001) and injury degree (p < 0.001) between the EPTE group (40 patients) and non-EPTE group (146 patients). Logistic regression analysis showed that the injury site, injury type and injury degree were the main risk factors for EPTE. The odds ratio values of injury site, injury type and injury degree were 1.977 (1.473–2.679), 2.096 (1.543–2.842) and 2.376 (1.864–3.609), respectively. The logistic regression equation was P = Exp (-1.473 + 0.698 × injury site + 0.717 × injury type + 0.935 × injury degree). The sensitivity and specificity of injury site, injury type and injury degree for predicting EPTE were 79.2% and 80.5%, 78.9% and 85.7% and 84.2% and 81.0%, respectively. The analysis of prognosis showed that the Glasgow Outcome Scale/Activity of Daily Living Scale scores in the EPTE group were significantly lower than those in non-EPTE group (p < 0.05). Conclusions Injury site, injury type and injury degree are the main risk factors for EPTE. The prognosis of patients with traumatic brain injury can be affected by EPTE.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019000600375&lng=en&tlng=enEpilepsy, post-traumaticrisk factorslogistic modelsprognosis |
| spellingShingle | Zaiming LIU Qianxue CHEN Zhibiao CHEN Junmin WANG Daofeng TIAN Long WANG Baohui LIU Shenqi ZHANG Clinical analysis on risk factors and prognosis of early post-traumatic epilepsy Arquivos de Neuro-Psiquiatria Epilepsy, post-traumatic risk factors logistic models prognosis |
| title | Clinical analysis on risk factors and prognosis of early post-traumatic epilepsy |
| title_full | Clinical analysis on risk factors and prognosis of early post-traumatic epilepsy |
| title_fullStr | Clinical analysis on risk factors and prognosis of early post-traumatic epilepsy |
| title_full_unstemmed | Clinical analysis on risk factors and prognosis of early post-traumatic epilepsy |
| title_short | Clinical analysis on risk factors and prognosis of early post-traumatic epilepsy |
| title_sort | clinical analysis on risk factors and prognosis of early post traumatic epilepsy |
| topic | Epilepsy, post-traumatic risk factors logistic models prognosis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019000600375&lng=en&tlng=en |
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