Comparative assessment of line probe assays and targeted next-generation sequencing in drug-resistant tuberculosis diagnosisResearch in context

Comparative assessment of line probe assays and targeted next-generation sequencing in drug-resistant tuberculosis diagnosisResearch in context

Summary: Background: Rapid and accurate detection of drug-resistant tuberculosis (DR-TB) is crucial for ensuring effective treatment, halting transmission and preventing the amplification of resistance. Comparative evaluations of molecular diagnostic assays in high-burden settings are essential for...

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Main Authors: Giovanna Carpi, Marva Seifert, Andres De la Rossa, Swapna Uplekar, Camilla Rodrigues, Nestani Tukvadze, Shaheed V. Omar, Anita Suresh, Timothy C. Rodwell, Rebecca E. Colman
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:EBioMedicine
Subjects:
Targeted NGS
tNGS
Sequencing
Drug resistance
Tuberculosis
Line probe assay
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425003196
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