Results dissemination of registered clinical trials across Polish academic institutions: a cross-sectional analysis
Objectives To establish the rates of publication and reporting of results for interventional clinical trials across Polish academic medical centres (AMCs) completed between 2009 and 2013. We aim also to compare the publication and reporting success between adult and paediatric trials.Design Cross-se...
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| Format: | Article |
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BMJ Publishing Group
2020-01-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/10/1/e034666.full |
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| author | Daniel Strech Karolina Strzebonska Mateusz T Wasylewski Lucja Zaborowska Nico Riedel Susanne Wieschowski Marcin Waligora |
| author_facet | Daniel Strech Karolina Strzebonska Mateusz T Wasylewski Lucja Zaborowska Nico Riedel Susanne Wieschowski Marcin Waligora |
| author_sort | Daniel Strech |
| collection | DOAJ |
| description | Objectives To establish the rates of publication and reporting of results for interventional clinical trials across Polish academic medical centres (AMCs) completed between 2009 and 2013. We aim also to compare the publication and reporting success between adult and paediatric trials.Design Cross-sectional study.Setting AMCs in Poland.Participants AMCs with interventional trials registered on ClinicalTrials.gov.Main outcome measure Results reporting on ClinicalTrials.gov and publishing via journal publication.Results We identified 305 interventional clinical trials registered on ClinicalTrials.gov, completed between 2009 and 2013 and affiliated with at least one AMC. Overall, 243 of the 305 trials (79.7%) had been published as articles or posted their summary results on ClinicalTrials.gov. Results were posted within a year of study completion and/or published within 2 years of study completion for 131 trials (43.0%). Dissemination by both posting and publishing results in a timely manner was achieved by four trials (1.3%).Conclusions Our cross-sectional analysis revealed that Polish AMCs fail to meet the expectation for timely disseminating the findings of all interventional clinical trials. Delayed dissemination and non-dissemination of trial results negatively affects decisions in healthcare. |
| format | Article |
| id | doaj-art-8dadc72e4f3c45cb9d2814be523d0911 |
| institution | OA Journals |
| issn | 2044-6055 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-8dadc72e4f3c45cb9d2814be523d09112025-08-20T02:19:34ZengBMJ Publishing GroupBMJ Open2044-60552020-01-0110110.1136/bmjopen-2019-034666Results dissemination of registered clinical trials across Polish academic institutions: a cross-sectional analysisDaniel Strech0Karolina Strzebonska1Mateusz T Wasylewski2Lucja Zaborowska3Nico Riedel4Susanne Wieschowski5Marcin Waligora6QUEST Center for Responsible Research, Berlin Institute of Health at Charité, Berlin, GermanyREMEDY, Research Ethics in Medicine Study Group, Department of Philosophy and Bioethics, Jagiellonian University Medical College, Krakow, PolandREMEDY, Research Ethics in Medicine Study Group, Department of Philosophy and Bioethics, Jagiellonian University Medical College, Krakow, PolandREMEDY, Research Ethics in Medicine Study Group, Department of Philosophy and Bioethics, Jagiellonian University Medical College, Krakow, PolandQUEST Center for Transforming Biomedical Research, Berlin Institute of Health, Berlin, GermanyInstitute for Ethics, History and Philosophy of Medicine, Hannover Medical School, Hannover, GermanyREMEDY, Research Ethics in Medicine Study Group, Department of Philosophy and Bioethics, Jagiellonian University Medical College, Krakow, PolandObjectives To establish the rates of publication and reporting of results for interventional clinical trials across Polish academic medical centres (AMCs) completed between 2009 and 2013. We aim also to compare the publication and reporting success between adult and paediatric trials.Design Cross-sectional study.Setting AMCs in Poland.Participants AMCs with interventional trials registered on ClinicalTrials.gov.Main outcome measure Results reporting on ClinicalTrials.gov and publishing via journal publication.Results We identified 305 interventional clinical trials registered on ClinicalTrials.gov, completed between 2009 and 2013 and affiliated with at least one AMC. Overall, 243 of the 305 trials (79.7%) had been published as articles or posted their summary results on ClinicalTrials.gov. Results were posted within a year of study completion and/or published within 2 years of study completion for 131 trials (43.0%). Dissemination by both posting and publishing results in a timely manner was achieved by four trials (1.3%).Conclusions Our cross-sectional analysis revealed that Polish AMCs fail to meet the expectation for timely disseminating the findings of all interventional clinical trials. Delayed dissemination and non-dissemination of trial results negatively affects decisions in healthcare.https://bmjopen.bmj.com/content/10/1/e034666.full |
| spellingShingle | Daniel Strech Karolina Strzebonska Mateusz T Wasylewski Lucja Zaborowska Nico Riedel Susanne Wieschowski Marcin Waligora Results dissemination of registered clinical trials across Polish academic institutions: a cross-sectional analysis BMJ Open |
| title | Results dissemination of registered clinical trials across Polish academic institutions: a cross-sectional analysis |
| title_full | Results dissemination of registered clinical trials across Polish academic institutions: a cross-sectional analysis |
| title_fullStr | Results dissemination of registered clinical trials across Polish academic institutions: a cross-sectional analysis |
| title_full_unstemmed | Results dissemination of registered clinical trials across Polish academic institutions: a cross-sectional analysis |
| title_short | Results dissemination of registered clinical trials across Polish academic institutions: a cross-sectional analysis |
| title_sort | results dissemination of registered clinical trials across polish academic institutions a cross sectional analysis |
| url | https://bmjopen.bmj.com/content/10/1/e034666.full |
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