Tailored guidance to apply the Estimand framework to Trials within Cohorts (TwiCs) studies

Tailored guidance to apply the Estimand framework to Trials within Cohorts (TwiCs) studies

Objective: The estimand framework offers a structured approach to define the treatment effect to be estimated in a clinical study. Defining the estimand upfront helps formulating the research question and informs study design, data collection and statistical analysis methods. Since the Trials within...

Full description

Saved in:
Bibliographic Details
Main Authors: R. Gal, R. Kessels, K. Luijken, L.A. Daamen, D.R. Mink van der Molen, S.A.M. Gernaat, A.M. May, H.M. Verkooijen, P.M. van de Ven
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Global Epidemiology
Subjects:
Trials within Cohorts study
TwiCs
Cohort multiple randomized controlled trial
cmRCT
Estimand
Intercurrent events
Online Access:http://www.sciencedirect.com/science/article/pii/S2590113324000294
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2590113324000294

Similar Items