Medium-vessel vasculitis following COVID-19 moderna (mRNA-1273) vaccination and the utility of PET-CT as a diagnostic tool: a case report
Abstract There have been several case reports of COVID-19 “BNT162b2” (Pfizer-BioNTech) and “mRNA-1273” (Moderna) vaccination associated small and medium vessel vasculitis described in the literature however none have had 18F-FDG Positron Emission Tomography scans (PET/CT) performed for diagnosis. We...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-04-01
|
| Series: | EJNMMI Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s41824-025-00247-7 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Abstract There have been several case reports of COVID-19 “BNT162b2” (Pfizer-BioNTech) and “mRNA-1273” (Moderna) vaccination associated small and medium vessel vasculitis described in the literature however none have had 18F-FDG Positron Emission Tomography scans (PET/CT) performed for diagnosis. We report the case of a 57-year-old Caucasian male patient from Australia where 18F-FDG PET/CT scanning facilitated early detection of a medium-vessel vasculitis following Moderna (mRNA-1273) COVID-19 vaccination. The diagnosis would otherwise have been difficult and allowed exclusion of alternative diagnoses and sparing of more invasive investigations such as muscle biopsy. Our case highlights the development of a medium vessel vasculitis following mRNA based COVID-19 vaccination and demonstrates the utility of 18F-FDG PET/CT as an excellent non-invasive test for the detection of this serious rare and often difficult to diagnose condition. |
|---|---|
| ISSN: | 3005-074X |