Transcutaneous auricular vagus nerve stimulation alleviates inflammation-induced depression by modulating peripheral-central inflammatory cytokines and the NF-κB pathway in rats

Transcutaneous auricular vagus nerve stimulation alleviates inflammation-induced depression by modulating peripheral-central inflammatory cytokines and the NF-κB pathway in rats

ObjectivesThis study aims to investigate the mechanisms of transcutaneous auricular vagus nerve stimulation (taVNS) in a lipopolysaccharide (LPS)-induced acute inflammatory depression model in rats, focusing on the regulation of peripheral pro- and anti-inflammatory cytokines and the effects on the...

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Bibliographic Details
Main Authors: Xingke Song, Haohan Zhu, Zijie Chen, Yifei Wang, Jinling Zhang, Yu Wang, Peijing Rong, Junying Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
transcutaneous auricular vagus nerve stimulation
inflammation
NF-κB
LPS
depression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1536056/full
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