Germ cell quantification in human fetal and prepubertal testis tissues: a comparison of current methodologies

Germ cell quantification in human fetal and prepubertal testis tissues: a comparison of current methodologies

Methods to quantify germ cell number in human immature testicular tissues are essential to evaluate the impact of chemotherapy exposures and to optimise cryopreservation protocols used in fertility preservation for prepubertal boys. Established quantification methods rely on the presence of round tu...

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Bibliographic Details
Main Authors: Emma Kearney, David Greenald, Gabriele Matilionyte, Sheila Lane, Melissa D Tharmalingam, Jill Davies, Jan-Bernd Stukenborg, Grace Forsyth, Rod T Mitchell
Format: Article
Language:English
Published: Bioscientifica 2025-02-01
Series:Reproduction and Fertility
Subjects:
human
testis
cisplatin
carboplatin
prepubertal
fetal
fertility
germ cells
gonocytes
spermatogonia
cell quantification
Online Access:https://raf.bioscientifica.com/view/journals/raf/6/1/RAF-24-0116.xml
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