Decreased complement 4 and interleukin-10 as biomarkers in aqueous humour for non-exudative age-related macular degeneration: a case control study

Decreased complement 4 and interleukin-10 as biomarkers in aqueous humour for non-exudative age-related macular degeneration: a case control study

Abstract Background The development of age-related macular degeneration (AMD) is influenced by risk factors that contribute to inflammatory processes, cellular stress responses, and a dysregulation of the complement system. Given the incomplete understanding of the pathogenesis of AMD and the necess...

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Main Authors: Juliane Schikora, Aaron Dort, Hannah N. Wolf, Mihály Józsi, Richard B. Pouw, Thomas Bertelmann, Dirk Bahlmann, Christian van Oterendorp, Nicolas Feltgen, Hans Hoerauf, Diana Pauly, Jannis Klemming
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Translational Medicine
Subjects:
Aqueous fluid
Biomarker
Chemokine
Complement regulation
Cytokine
Drusen
Online Access:https://doi.org/10.1186/s12967-024-05909-x
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