Allogeneic CART progress: platforms, current progress and limitations

Allogeneic CART progress: platforms, current progress and limitations

Allogenic chimeric antigen receptor T (CAR-T) cells have advantages compared to autologous T cell therapies such as availability cells for production, a suitable HLA-matched donor (if graft-vs-host-disease and rejection effects are to be avoided and also lower risks associated with transduction meth...

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Bibliographic Details
Main Authors:	Ameneh Shokati, Maryam Sanjari-Pour, Mahshid Akhavan Rahnama, Saghar Hoseinzadeh, Mohammad Vaezi, Mohammad Ahmadvand
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Immunology
Subjects:	allogeneic CAR T cells editing technology non-editing technology off-the-shelf CART cell graft-versus-host disease
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1557157/full
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