Gender Differences in Fat Distribution and Inflammatory Markers among Arabs
Recent studies from the Gulf region suggest that compared to men, women have a greater risk of developing metabolic syndrome (MeS). Objective. To investigate gender differences in body composition, adipokines, inflammatory markers, and aerobic fitness in a cohort of healthy Qatari adults. Participan...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2013/497324 |
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| _version_ | 1849400741314166784 |
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| author | Abdulaziz Farooq Wade L. Knez Kelly Knez Asma Al-Noaimi Justin Grantham Vidya Mohamed-Ali |
| author_facet | Abdulaziz Farooq Wade L. Knez Kelly Knez Asma Al-Noaimi Justin Grantham Vidya Mohamed-Ali |
| author_sort | Abdulaziz Farooq |
| collection | DOAJ |
| description | Recent studies from the Gulf region suggest that compared to men, women have a greater risk of developing metabolic syndrome (MeS). Objective. To investigate gender differences in body composition, adipokines, inflammatory markers, and aerobic fitness in a cohort of healthy Qatari adults. Participants. Healthy Qatari (n=58) were matched for age, gender, and body mass index. Methods. Body composition and regional fat distribution were determined by dual-energy X-ray absorptiometry and computerized tomography. Laboratory assessments included serum levels of fasting glucose, insulin, lipid profile analysis, adipokines, and inflammatory markers. Subjects were also evaluated for aerobic fitness. Results. Women had more adipose tissue in the total abdominal (P=0.04) and abdominal subcutaneous (P=0.07) regions compared to men. Waist circumference and indices of insulin sensitivity were similar; however, women had a more favourable lipid profile than men. Serum adiponectin and leptin levels were significantly higher in women, whereas inflammatory profiles were not different between men and women. Aerobic fitness was lower in women and was associated with abdominal fat accumulation. Conclusion. In premenopausal women, higher levels of adiponectin may support maintenance of insulin sensitivity and normolipidemia despite greater adiposity. However, poor aerobic fitness combined with abdominal fat accumulation may explain their greater future risk of MeS compared with men. |
| format | Article |
| id | doaj-art-8d82629eadf7448aae752c0511a522c9 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-8d82629eadf7448aae752c0511a522c92025-08-20T03:37:56ZengWileyMediators of Inflammation0962-93511466-18612013-01-01201310.1155/2013/497324497324Gender Differences in Fat Distribution and Inflammatory Markers among ArabsAbdulaziz Farooq0Wade L. Knez1Kelly Knez2Asma Al-Noaimi3Justin Grantham4Vidya Mohamed-Ali5Aspetar, Qatar Orthopaedic and Sports Medicine Hospital, P.O. Box 29222, Doha, QatarAspetar, Qatar Orthopaedic and Sports Medicine Hospital, P.O. Box 29222, Doha, QatarAspetar, Qatar Orthopaedic and Sports Medicine Hospital, P.O. Box 29222, Doha, QatarSupreme Council of Health, P.O. Box 7744, Doha, QatarAspire Zone Foundation, P.O. Box 93097, Doha, QatarUniversity College London, 5 University Street, London WC1E 6JF, UKRecent studies from the Gulf region suggest that compared to men, women have a greater risk of developing metabolic syndrome (MeS). Objective. To investigate gender differences in body composition, adipokines, inflammatory markers, and aerobic fitness in a cohort of healthy Qatari adults. Participants. Healthy Qatari (n=58) were matched for age, gender, and body mass index. Methods. Body composition and regional fat distribution were determined by dual-energy X-ray absorptiometry and computerized tomography. Laboratory assessments included serum levels of fasting glucose, insulin, lipid profile analysis, adipokines, and inflammatory markers. Subjects were also evaluated for aerobic fitness. Results. Women had more adipose tissue in the total abdominal (P=0.04) and abdominal subcutaneous (P=0.07) regions compared to men. Waist circumference and indices of insulin sensitivity were similar; however, women had a more favourable lipid profile than men. Serum adiponectin and leptin levels were significantly higher in women, whereas inflammatory profiles were not different between men and women. Aerobic fitness was lower in women and was associated with abdominal fat accumulation. Conclusion. In premenopausal women, higher levels of adiponectin may support maintenance of insulin sensitivity and normolipidemia despite greater adiposity. However, poor aerobic fitness combined with abdominal fat accumulation may explain their greater future risk of MeS compared with men.http://dx.doi.org/10.1155/2013/497324 |
| spellingShingle | Abdulaziz Farooq Wade L. Knez Kelly Knez Asma Al-Noaimi Justin Grantham Vidya Mohamed-Ali Gender Differences in Fat Distribution and Inflammatory Markers among Arabs Mediators of Inflammation |
| title | Gender Differences in Fat Distribution and Inflammatory Markers among Arabs |
| title_full | Gender Differences in Fat Distribution and Inflammatory Markers among Arabs |
| title_fullStr | Gender Differences in Fat Distribution and Inflammatory Markers among Arabs |
| title_full_unstemmed | Gender Differences in Fat Distribution and Inflammatory Markers among Arabs |
| title_short | Gender Differences in Fat Distribution and Inflammatory Markers among Arabs |
| title_sort | gender differences in fat distribution and inflammatory markers among arabs |
| url | http://dx.doi.org/10.1155/2013/497324 |
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