Prognostic implications of alternative splicing events and key splicing factors in head and neck squamous cell carcinoma

Prognostic implications of alternative splicing events and key splicing factors in head and neck squamous cell carcinoma

Abstract The incidence of head and neck squamous cell carcinoma (HNSCC) remains high, accompanied by low 5-year survival rates. Identifying prognostic factors is essential for advancing personalized treatment approaches. Increasing evidence implicates aberrant alternative splicing (AS) plays a key r...

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Bibliographic Details
Main Authors: Siyi He, Jiali Meng, Chunyan Liang, Yiru Wang, Xinling Qin, Lulu Huang, Rensheng Wang, Weimei Huang
Format: Article
Language:English
Published: Springer 2025-03-01
Series:Discover Oncology
Subjects:
HNSCC
Alternative splicing
Splicing factor
Prognostic model
DDX39B
PRPF39
Online Access:https://doi.org/10.1007/s12672-025-02214-x
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