Impact of differential detection of TM6SF2 rs58542926 mutation in circulating tumor DNA versus peripheral blood cells on hepatocellular carcinoma patients

Impact of differential detection of TM6SF2 rs58542926 mutation in circulating tumor DNA versus peripheral blood cells on hepatocellular carcinoma patients

Abstract This study aimed to investigate the differential distribution of the genotypes of the TM6SF2 rs58542926 polymorphism in circulating tumor DNA (ctDNA) versus peripheral blood cells (PBMC) and its association with the development of hepatocellular carcinoma (HCC) in patients infected with the...

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Bibliographic Details
Main Authors: Samar Samir Youssef, Eman Abd El Razek Abbas, Mohamed Hassany, Aya Shaaban Ragheb Shaaban, Eman Elsayed Abass Mohammed, Tamer Elbaz
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
Subjects:
Hepatocellular carcinoma
HCC
TM6SF2 mutation
HCV infection
Online Access:https://doi.org/10.1007/s12672-025-02812-9
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