Structure and biological functions of milk caseins

Caseins, which are contained in milk, play a significant role in the development of clinical symptoms of allergic reactions in adults and children. To date, the properties of caseins have been studied, their primary structure has been identified. However, despite available scientific reviews and ori...

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Main Authors: Stanislava Yu. Petrova, Svetlana V. Khlgatian, Olga Yu. Emelyanova, Larisa A. Pishulina, Valentina M. Berzhets
Format: Article
Language:English
Published: Limited liability company «Science and Innovations» (Saratov) 2022-06-01
Series:Russian Open Medical Journal
Subjects:
Online Access:https://romj.org/node/465
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author Stanislava Yu. Petrova
Svetlana V. Khlgatian
Olga Yu. Emelyanova
Larisa A. Pishulina
Valentina M. Berzhets
author_facet Stanislava Yu. Petrova
Svetlana V. Khlgatian
Olga Yu. Emelyanova
Larisa A. Pishulina
Valentina M. Berzhets
author_sort Stanislava Yu. Petrova
collection DOAJ
description Caseins, which are contained in milk, play a significant role in the development of clinical symptoms of allergic reactions in adults and children. To date, the properties of caseins have been studied, their primary structure has been identified. However, despite available scientific reviews and original articles, an issue of the structural organization of milk casein micelles and their biological functions is still very controversial. In this regard, the proposed review is relevant, since it most fully reflects current information about various types of caseins, their physicochemical and immunobiological properties, and analyzes in detail the existing theories on the structural organization of casein micelles. Of particular interest in our review are the data on the comparative analysis of the structure and properties of caseins in both human breast milk and cow’s milk, as well as the section dealing with the allergenic activity of cow’s milk caseins and their cross-reactivity with milk proteins of other mammalian species. The objective of this review is to summarize current data on the structure and properties of casein proteins, and to determine their role in the formation of sensitization to dairy products.
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publisher Limited liability company «Science and Innovations» (Saratov)
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series Russian Open Medical Journal
spelling doaj-art-8d54716a7121428eba2afbe46c1f66dd2025-08-20T02:03:05ZengLimited liability company «Science and Innovations» (Saratov)Russian Open Medical Journal2304-34152022-06-01112e020910.15275/rusomj.2022.0209Structure and biological functions of milk caseinsStanislava Yu. PetrovaSvetlana V. KhlgatianOlga Yu. EmelyanovaLarisa A. PishulinaValentina M. BerzhetsCaseins, which are contained in milk, play a significant role in the development of clinical symptoms of allergic reactions in adults and children. To date, the properties of caseins have been studied, their primary structure has been identified. However, despite available scientific reviews and original articles, an issue of the structural organization of milk casein micelles and their biological functions is still very controversial. In this regard, the proposed review is relevant, since it most fully reflects current information about various types of caseins, their physicochemical and immunobiological properties, and analyzes in detail the existing theories on the structural organization of casein micelles. Of particular interest in our review are the data on the comparative analysis of the structure and properties of caseins in both human breast milk and cow’s milk, as well as the section dealing with the allergenic activity of cow’s milk caseins and their cross-reactivity with milk proteins of other mammalian species. The objective of this review is to summarize current data on the structure and properties of casein proteins, and to determine their role in the formation of sensitization to dairy products.https://romj.org/node/465cow’s milkhuman breast milkcasein micelleβ-caseinκ-casein
spellingShingle Stanislava Yu. Petrova
Svetlana V. Khlgatian
Olga Yu. Emelyanova
Larisa A. Pishulina
Valentina M. Berzhets
Structure and biological functions of milk caseins
Russian Open Medical Journal
cow’s milk
human breast milk
casein micelle
β-casein
κ-casein
title Structure and biological functions of milk caseins
title_full Structure and biological functions of milk caseins
title_fullStr Structure and biological functions of milk caseins
title_full_unstemmed Structure and biological functions of milk caseins
title_short Structure and biological functions of milk caseins
title_sort structure and biological functions of milk caseins
topic cow’s milk
human breast milk
casein micelle
β-casein
κ-casein
url https://romj.org/node/465
work_keys_str_mv AT stanislavayupetrova structureandbiologicalfunctionsofmilkcaseins
AT svetlanavkhlgatian structureandbiologicalfunctionsofmilkcaseins
AT olgayuemelyanova structureandbiologicalfunctionsofmilkcaseins
AT larisaapishulina structureandbiologicalfunctionsofmilkcaseins
AT valentinamberzhets structureandbiologicalfunctionsofmilkcaseins