Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer's model of adult zebrafish brain.

Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer's model of adult zebrafish brain.

It was recently suggested that supplying the brain with new neurons could counteract Alzheimer's disease (AD). This provocative idea requires further testing in experimental models in which the molecular basis of disease-induced neuronal regeneration could be investigated. We previously found t...

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Main Authors: Prabesh Bhattarai, Mehmet Ilyas Cosacak, Violeta Mashkaryan, Sevgican Demir, Stanislava Dimitrova Popova, Nambirajan Govindarajan, Kerstin Brandt, Yixin Zhang, Weipang Chang, Konstantinos Ampatzis, Caghan Kizil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3000585&type=printable
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