Accuracy comparison of six intraocular lens formulas using total and standard keratometry measurements with the iolmaster 700
Abstract This study aimed to evaluate the accuracy of six intraocular lens (IOL) calculation formulas using total keratometry (TK) and standard keratometry (K) measurements from the IOLMaster 700 in various ocular subgroups. A total of 212 eyes were analyzed. The mean absolute error (MAE), standard...
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Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-11332-z |
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| author | Shuang Ni Jingwen Wang Danni Lyu Zhe Xu Jing-Wei Xu Sha Zhu Yixuan Feng Ce Shi Wen Xu |
| author_facet | Shuang Ni Jingwen Wang Danni Lyu Zhe Xu Jing-Wei Xu Sha Zhu Yixuan Feng Ce Shi Wen Xu |
| author_sort | Shuang Ni |
| collection | DOAJ |
| description | Abstract This study aimed to evaluate the accuracy of six intraocular lens (IOL) calculation formulas using total keratometry (TK) and standard keratometry (K) measurements from the IOLMaster 700 in various ocular subgroups. A total of 212 eyes were analyzed. The mean absolute error (MAE), standard deviation (SD) of prediction error, and the median absolute error (MedAE) were calculated for each formula. and the prediction accuracy was compared across different subgroups categorized by axial length (AL), anterior chamber depth (ACD), lens thickness (LT), and other ocular parameters. Results showed that the Barrett Universal II (BU II) formula consistently had the lowest MAEs and MedAEs in the overall sample and most subgroups. The BU II formula performed particularly well in subgroups with thin LT when using TK mode and in medium LT subgroups using K mode. Comparison between TK and K modes showed no consistent superiority, with each mode outperforming the other in specific subgroups. The accuracy of the BU II formula was not influenced by ocular parameters, suggesting its robustness across different patient groups. In conclusion, the BU II formula demonstrated superior accuracy compared to other formulas, especially in specific subgroups, and its performance remained consistent regardless of ocular measurement variations. |
| format | Article |
| id | doaj-art-8d4adbbf694d4512a6d0ed41cd7709c2 |
| institution | DOAJ |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nature Portfolio |
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| spelling | doaj-art-8d4adbbf694d4512a6d0ed41cd7709c22025-08-20T03:05:26ZengNature PortfolioScientific Reports2045-23222025-07-0115111310.1038/s41598-025-11332-zAccuracy comparison of six intraocular lens formulas using total and standard keratometry measurements with the iolmaster 700Shuang Ni0Jingwen Wang1Danni Lyu2Zhe Xu3Jing-Wei Xu4Sha Zhu5Yixuan Feng6Ce Shi7Wen Xu8Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang UniversityAbstract This study aimed to evaluate the accuracy of six intraocular lens (IOL) calculation formulas using total keratometry (TK) and standard keratometry (K) measurements from the IOLMaster 700 in various ocular subgroups. A total of 212 eyes were analyzed. The mean absolute error (MAE), standard deviation (SD) of prediction error, and the median absolute error (MedAE) were calculated for each formula. and the prediction accuracy was compared across different subgroups categorized by axial length (AL), anterior chamber depth (ACD), lens thickness (LT), and other ocular parameters. Results showed that the Barrett Universal II (BU II) formula consistently had the lowest MAEs and MedAEs in the overall sample and most subgroups. The BU II formula performed particularly well in subgroups with thin LT when using TK mode and in medium LT subgroups using K mode. Comparison between TK and K modes showed no consistent superiority, with each mode outperforming the other in specific subgroups. The accuracy of the BU II formula was not influenced by ocular parameters, suggesting its robustness across different patient groups. In conclusion, the BU II formula demonstrated superior accuracy compared to other formulas, especially in specific subgroups, and its performance remained consistent regardless of ocular measurement variations.https://doi.org/10.1038/s41598-025-11332-zIntraocular lens (IOL)Total keratometry (TK)Standard keratometry (K)IOLMaster 700IOL formula |
| spellingShingle | Shuang Ni Jingwen Wang Danni Lyu Zhe Xu Jing-Wei Xu Sha Zhu Yixuan Feng Ce Shi Wen Xu Accuracy comparison of six intraocular lens formulas using total and standard keratometry measurements with the iolmaster 700 Scientific Reports Intraocular lens (IOL) Total keratometry (TK) Standard keratometry (K) IOLMaster 700 IOL formula |
| title | Accuracy comparison of six intraocular lens formulas using total and standard keratometry measurements with the iolmaster 700 |
| title_full | Accuracy comparison of six intraocular lens formulas using total and standard keratometry measurements with the iolmaster 700 |
| title_fullStr | Accuracy comparison of six intraocular lens formulas using total and standard keratometry measurements with the iolmaster 700 |
| title_full_unstemmed | Accuracy comparison of six intraocular lens formulas using total and standard keratometry measurements with the iolmaster 700 |
| title_short | Accuracy comparison of six intraocular lens formulas using total and standard keratometry measurements with the iolmaster 700 |
| title_sort | accuracy comparison of six intraocular lens formulas using total and standard keratometry measurements with the iolmaster 700 |
| topic | Intraocular lens (IOL) Total keratometry (TK) Standard keratometry (K) IOLMaster 700 IOL formula |
| url | https://doi.org/10.1038/s41598-025-11332-z |
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