Apolipoprotein E-ε4 allele is associated with perihematomal brain edema and poor outcomes in patients with intracerebral hemorrhage

Apolipoprotein E-ε4 allele is associated with perihematomal brain edema and poor outcomes in patients with intracerebral hemorrhage

Abstract Intracerebral hemorrhage (ICH) poses significant disability and mortality risks and perihematomal edema (PHE) plays a crucial role in ICH prognosis. The ApoE-ε4 allele has been implicated in exacerbating PHE and influencing neurological recovery post-ICH, yet, this specific association has...

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Bibliographic Details
Main Authors: Lei Huang, Qian Wu, Fei Ye, Wei Che, Xu Zhao, ChaoZhen Yang, Siying Ren, Guofeng Wu, Likun Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Apolipoprotein E gene
Perihematomal edema
Outcome
Intracerebral hemorrhage
Online Access:https://doi.org/10.1038/s41598-025-89868-3
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