Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases
Increasing data demonstrates that inflammation participates in the pathophysiology of neurodegenerative diseases. Among the different inflammatory mediators involved, prostaglandins play an important role. The effects induced by prostaglandins might be mediated by activation of their known receptors...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2012/946813 |
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| _version_ | 1832559843157737472 |
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| author | Isabel Vieira de Assis Lima Leandro Francisco Silva Bastos Marcelo Limborço-Filho Bernd L. Fiebich Antonio Carlos Pinheiro de Oliveira |
| author_facet | Isabel Vieira de Assis Lima Leandro Francisco Silva Bastos Marcelo Limborço-Filho Bernd L. Fiebich Antonio Carlos Pinheiro de Oliveira |
| author_sort | Isabel Vieira de Assis Lima |
| collection | DOAJ |
| description | Increasing data demonstrates that inflammation participates in the pathophysiology of neurodegenerative diseases. Among the different inflammatory mediators involved, prostaglandins play an important role. The effects induced by prostaglandins might be mediated by activation of their known receptors or by nonclassical mechanisms. In the present paper, we discuss the evidences that link prostaglandins, as well as the enzymes that produce them, to some neurological diseases. |
| format | Article |
| id | doaj-art-8d41bec6f090442c833cc506f90ba053 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-8d41bec6f090442c833cc506f90ba0532025-02-03T01:29:04ZengWileyMediators of Inflammation0962-93511466-18612012-01-01201210.1155/2012/946813946813Role of Prostaglandins in Neuroinflammatory and Neurodegenerative DiseasesIsabel Vieira de Assis Lima0Leandro Francisco Silva Bastos1Marcelo Limborço-Filho2Bernd L. Fiebich3Antonio Carlos Pinheiro de Oliveira4Department of Pharmacology, Federal University of Minas Gerais, Avenida Antonio Carlos, 6627, 31270-901 Belo Horizonte, MG, BrazilDepartment of Physiology and Biophysics, Federal University of Minas Gerais, Avenida Antonio Carlos, 6627, 31270-901 Belo Horizonte, BrazilDepartment of Physiology and Biophysics, Federal University of Minas Gerais, Avenida Antonio Carlos, 6627, 31270-901 Belo Horizonte, BrazilDepartment of Psychiatry and Psychotherapy, University of Freiburg Medical School, Hauptstraße 5, 79104 Freiburg, GermanyDepartment of Pharmacology, Federal University of Minas Gerais, Avenida Antonio Carlos, 6627, 31270-901 Belo Horizonte, MG, BrazilIncreasing data demonstrates that inflammation participates in the pathophysiology of neurodegenerative diseases. Among the different inflammatory mediators involved, prostaglandins play an important role. The effects induced by prostaglandins might be mediated by activation of their known receptors or by nonclassical mechanisms. In the present paper, we discuss the evidences that link prostaglandins, as well as the enzymes that produce them, to some neurological diseases.http://dx.doi.org/10.1155/2012/946813 |
| spellingShingle | Isabel Vieira de Assis Lima Leandro Francisco Silva Bastos Marcelo Limborço-Filho Bernd L. Fiebich Antonio Carlos Pinheiro de Oliveira Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases Mediators of Inflammation |
| title | Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases |
| title_full | Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases |
| title_fullStr | Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases |
| title_full_unstemmed | Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases |
| title_short | Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases |
| title_sort | role of prostaglandins in neuroinflammatory and neurodegenerative diseases |
| url | http://dx.doi.org/10.1155/2012/946813 |
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