Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses
Graphical Abstract The hypothesis is discussed that prostate cancer marker lncRNA PCA3 was introduced into the human genome by an oncogenic virus, and that viral infection‐related mechanisms might underlie its overexpression and prostate cancer initiation and/or progression.
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Springer Nature
2017-07-01
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| Series: | EMBO Molecular Medicine |
| Online Access: | https://doi.org/10.15252/emmm.201708072 |
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| author | Andre A Teixeira Serena Marchiò Emmanuel Dias‐Neto Diana N Nunes Israel T da Silva Bryce Chackerian Marc Barry Richard C Lauer Ricardo J Giordano Richard L Sidman Cosette M Wheeler Webster K Cavenee Renata Pasqualini Wadih Arap |
| author_facet | Andre A Teixeira Serena Marchiò Emmanuel Dias‐Neto Diana N Nunes Israel T da Silva Bryce Chackerian Marc Barry Richard C Lauer Ricardo J Giordano Richard L Sidman Cosette M Wheeler Webster K Cavenee Renata Pasqualini Wadih Arap |
| author_sort | Andre A Teixeira |
| collection | DOAJ |
| description | Graphical Abstract The hypothesis is discussed that prostate cancer marker lncRNA PCA3 was introduced into the human genome by an oncogenic virus, and that viral infection‐related mechanisms might underlie its overexpression and prostate cancer initiation and/or progression. |
| format | Article |
| id | doaj-art-8d221eac6f144f378b13373e38c5f65b |
| institution | DOAJ |
| issn | 1757-4676 1757-4684 |
| language | English |
| publishDate | 2017-07-01 |
| publisher | Springer Nature |
| record_format | Article |
| series | EMBO Molecular Medicine |
| spelling | doaj-art-8d221eac6f144f378b13373e38c5f65b2025-08-20T03:06:00ZengSpringer NatureEMBO Molecular Medicine1757-46761757-46842017-07-019101327133010.15252/emmm.201708072Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic virusesAndre A Teixeira0Serena Marchiò1Emmanuel Dias‐Neto2Diana N Nunes3Israel T da Silva4Bryce Chackerian5Marc Barry6Richard C Lauer7Ricardo J Giordano8Richard L Sidman9Cosette M Wheeler10Webster K Cavenee11Renata Pasqualini12Wadih Arap13University of New Mexico Comprehensive Cancer CenterUniversity of New Mexico Comprehensive Cancer CenterLaboratory of Medical Genomics, A.C.Camargo Cancer CenterLaboratory of Medical Genomics, A.C.Camargo Cancer CenterLaboratory of Computational Biology, A.C.Camargo Cancer CenterDepartment of Molecular Genetics and Microbiology, University of New MexicoUniversity of New Mexico Comprehensive Cancer CenterUniversity of New Mexico Comprehensive Cancer CenterDepartment of Biochemistry, Chemistry Institute, University of São PauloDepartment of Neurology, Harvard Medical SchoolUniversity of New Mexico Comprehensive Cancer CenterLudwig Institute for Cancer Research, University of California‐San DiegoUniversity of New Mexico Comprehensive Cancer CenterUniversity of New Mexico Comprehensive Cancer CenterGraphical Abstract The hypothesis is discussed that prostate cancer marker lncRNA PCA3 was introduced into the human genome by an oncogenic virus, and that viral infection‐related mechanisms might underlie its overexpression and prostate cancer initiation and/or progression.https://doi.org/10.15252/emmm.201708072 |
| spellingShingle | Andre A Teixeira Serena Marchiò Emmanuel Dias‐Neto Diana N Nunes Israel T da Silva Bryce Chackerian Marc Barry Richard C Lauer Ricardo J Giordano Richard L Sidman Cosette M Wheeler Webster K Cavenee Renata Pasqualini Wadih Arap Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses EMBO Molecular Medicine |
| title | Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses |
| title_full | Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses |
| title_fullStr | Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses |
| title_full_unstemmed | Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses |
| title_short | Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses |
| title_sort | going viral linking the etiology of human prostate cancer to the pca3 long noncoding rna and oncogenic viruses |
| url | https://doi.org/10.15252/emmm.201708072 |
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