HEMODYNAMIC AND GAS EXCHANGE RESPONSE IN CHILDREN WITH CNS DISORDERS DURING PROCEDURAL SEDATION UNDERGOING COMPUTED TOMOGRAPHY

From the safety point of view, procedural sedation results in fairly frequent complications, typical of the anesthetics being used.The objective: to study the hemodynamics, gas exchange and the character of complications (respiratory disorders, agitation) when using thiopental sodium, ketamine and p...

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Main Authors: R. V. Zhdanov, E. V. Grigoriev
Format: Article
Language:Russian
Published: New Terra Publishing House 2019-01-01
Series:Вестник анестезиологии и реаниматологии
Subjects:
Online Access:https://www.vair-journal.com/jour/article/view/291
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author R. V. Zhdanov
E. V. Grigoriev
author_facet R. V. Zhdanov
E. V. Grigoriev
author_sort R. V. Zhdanov
collection DOAJ
description From the safety point of view, procedural sedation results in fairly frequent complications, typical of the anesthetics being used.The objective: to study the hemodynamics, gas exchange and the character of complications (respiratory disorders, agitation) when using thiopental sodium, ketamine and propofol during procedural sedation in the children with CNS disorders undergoing computed tomography.Subjects and methods. 90 patients at the age from 8 months to 10 years with the risk degree of II–III as per ASA who underwent computed tomography were enrolled in the study. The patients were divided into three groups depending on the anesthetic being used. Changes in hemodynamics, gas exchange and frequency of complications were analyzed.Results. Hypercapnia and reduced saturation were documented in the propofol group, which were the consequences of hypoventilation and they required the respiratory support in the form of oxygen insufflation through the face mask in 46.7% of cases or artificial pulmonary ventilation (30% of cases). In ketamine group, agitation was documented in 6% of cases.Conclusions. For procedural sedation in children with CNS disorders, thiopental sodium is the drug of choice, since it provides the least significant impact on hemodynamics, gas exchange and causes no complications.
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spelling doaj-art-8d214fb0707a451c83178d69ecf19ffb2025-08-20T03:23:07ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532019-01-01156334110.21292/2078-5658-2018-15-6-33-41278HEMODYNAMIC AND GAS EXCHANGE RESPONSE IN CHILDREN WITH CNS DISORDERS DURING PROCEDURAL SEDATION UNDERGOING COMPUTED TOMOGRAPHYR. V. Zhdanov0E. V. Grigoriev1Belyaev Kemerovo Regional Clinical Hospital; Kemerovo State Medical UniversityKemerovo State Medical UniversityFrom the safety point of view, procedural sedation results in fairly frequent complications, typical of the anesthetics being used.The objective: to study the hemodynamics, gas exchange and the character of complications (respiratory disorders, agitation) when using thiopental sodium, ketamine and propofol during procedural sedation in the children with CNS disorders undergoing computed tomography.Subjects and methods. 90 patients at the age from 8 months to 10 years with the risk degree of II–III as per ASA who underwent computed tomography were enrolled in the study. The patients were divided into three groups depending on the anesthetic being used. Changes in hemodynamics, gas exchange and frequency of complications were analyzed.Results. Hypercapnia and reduced saturation were documented in the propofol group, which were the consequences of hypoventilation and they required the respiratory support in the form of oxygen insufflation through the face mask in 46.7% of cases or artificial pulmonary ventilation (30% of cases). In ketamine group, agitation was documented in 6% of cases.Conclusions. For procedural sedation in children with CNS disorders, thiopental sodium is the drug of choice, since it provides the least significant impact on hemodynamics, gas exchange and causes no complications.https://www.vair-journal.com/jour/article/view/291anesthesiacardiac vascular systemgas exchangecomputed tomographychildrencns disorders
spellingShingle R. V. Zhdanov
E. V. Grigoriev
HEMODYNAMIC AND GAS EXCHANGE RESPONSE IN CHILDREN WITH CNS DISORDERS DURING PROCEDURAL SEDATION UNDERGOING COMPUTED TOMOGRAPHY
Вестник анестезиологии и реаниматологии
anesthesia
cardiac vascular system
gas exchange
computed tomography
children
cns disorders
title HEMODYNAMIC AND GAS EXCHANGE RESPONSE IN CHILDREN WITH CNS DISORDERS DURING PROCEDURAL SEDATION UNDERGOING COMPUTED TOMOGRAPHY
title_full HEMODYNAMIC AND GAS EXCHANGE RESPONSE IN CHILDREN WITH CNS DISORDERS DURING PROCEDURAL SEDATION UNDERGOING COMPUTED TOMOGRAPHY
title_fullStr HEMODYNAMIC AND GAS EXCHANGE RESPONSE IN CHILDREN WITH CNS DISORDERS DURING PROCEDURAL SEDATION UNDERGOING COMPUTED TOMOGRAPHY
title_full_unstemmed HEMODYNAMIC AND GAS EXCHANGE RESPONSE IN CHILDREN WITH CNS DISORDERS DURING PROCEDURAL SEDATION UNDERGOING COMPUTED TOMOGRAPHY
title_short HEMODYNAMIC AND GAS EXCHANGE RESPONSE IN CHILDREN WITH CNS DISORDERS DURING PROCEDURAL SEDATION UNDERGOING COMPUTED TOMOGRAPHY
title_sort hemodynamic and gas exchange response in children with cns disorders during procedural sedation undergoing computed tomography
topic anesthesia
cardiac vascular system
gas exchange
computed tomography
children
cns disorders
url https://www.vair-journal.com/jour/article/view/291
work_keys_str_mv AT rvzhdanov hemodynamicandgasexchangeresponseinchildrenwithcnsdisordersduringproceduralsedationundergoingcomputedtomography
AT evgrigoriev hemodynamicandgasexchangeresponseinchildrenwithcnsdisordersduringproceduralsedationundergoingcomputedtomography