Docosahexaenoic acid (DHA) supplementation attenuates changes in the concentration, phenotype, and response of immune peripheral blood cells in breast cancer patients undergoing neoadjuvant therapy. Secondary findings from the DHA-WIN trial

Docosahexaenoic acid (DHA) supplementation attenuates changes in the concentration, phenotype, and response of immune peripheral blood cells in breast cancer patients undergoing neoadjuvant therapy. Secondary findings from the DHA-WIN trial

Abstract Background Breast cancer neoadjuvant therapy may negatively impact the immune system. As a secondary outcome of the docosahexaenoic acid (DHA) for women with breast cancer in the neoadjuvant setting (DHA-WIN trial), we sought to assess the effects of an intervention with DHA on parameters o...

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Bibliographic Details
Main Authors: Jaqueline Munhoz, Marnie Newell, Susan Goruk, Sunita Ghosh, Dhruvesh Patel, Anil Abraham Joy, Gilbert Bigras, Vera Mazurak, Kerry S. Courneya, Denise G. Hemmings, Catherine J. Field
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Breast Cancer Research
Subjects:
Immune response
Pathological complete response
Long-chain polyunsaturated fatty acid
Cytokines
Immune phenotype
Online Access:https://doi.org/10.1186/s13058-025-02048-z
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