Remote versus face-to-face home-based exercise programme in people with amyotrophic lateral sclerosis: protocol for a randomised clinical trial
Introduction Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease with variable and complex clinical manifestations that requires a multidisciplinary approach. However, face-to-face treatment in this population may experience barriers, such as difficulty accessing physical...
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BMJ Publishing Group
2022-05-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/5/e056323.full |
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| author | Tatiana Souza Ribeiro Aline Alves de Souza Stephano Tomaz da Silva Karen de Medeiros Pondofe Vanessa Regiane Resqueti Luciana Protásio de Melo Ricardo Alexsandro de Medeiros Valentim |
| author_facet | Tatiana Souza Ribeiro Aline Alves de Souza Stephano Tomaz da Silva Karen de Medeiros Pondofe Vanessa Regiane Resqueti Luciana Protásio de Melo Ricardo Alexsandro de Medeiros Valentim |
| author_sort | Tatiana Souza Ribeiro |
| collection | DOAJ |
| description | Introduction Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease with variable and complex clinical manifestations that requires a multidisciplinary approach. However, face-to-face treatment in this population may experience barriers, such as difficulty accessing physical therapists or other professionals. As a result, strategies (eg, telerehabilitation) emerged to facilitate treatment and physical therapy monitoring. This study aims to evaluate the effects of remote versus face-to-face home-based exercise programmes on clinical outcomes and treatment adherence of people with ALS.Methods and analysis This is a single-blind randomised clinical trial protocol that will include 44 people with clinical diagnosis of ALS at any clinical stage and aged between 18 and 80 years. Participants will be randomised into two groups after face-to-face evaluation and perform a home-based exercise programme three times a week for 6 months. A physical therapist will monitor the exercise programme once a week remotely (phone calls—experimental group) or face-to-face (home visits—control group). The primary outcome measure will be functional capacity (Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised). Secondary outcomes will include disease severity (Amyotrophic Lateral Sclerosis Severity Scale), fatigue (Fatigue Severity Scale), pain (Visual Analogue Scale and body pain diagram), adverse events and adherence rate. Outcomes will be initially evaluated face-to-face and revaluated remotely every 2 months and 1 month after interventions. Linear mixed models will compare outcome measures between groups and evaluations (α=5%).Ethics and dissemination This study was approved by the research ethics committee of Hospital Universitário Onofre Lopes/Universidade Federal do Rio Grande do Norte (no. 3735479). We expect to identify the effects of an exercise programme developed according to ALS stages and associated with remote or face-to-face monitoring on clinical outcomes using revaluations and follow-up after interventions.Trial registration number Brazilian Registry Clinical Trials (RBR-10z9pgfv). |
| format | Article |
| id | doaj-art-8d1eefa0e3c844f3995e61d4db088002 |
| institution | OA Journals |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-05-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-8d1eefa0e3c844f3995e61d4db0880022025-08-20T02:15:12ZengBMJ Publishing GroupBMJ Open2044-60552022-05-0112510.1136/bmjopen-2021-056323Remote versus face-to-face home-based exercise programme in people with amyotrophic lateral sclerosis: protocol for a randomised clinical trialTatiana Souza Ribeiro0Aline Alves de Souza1Stephano Tomaz da Silva2Karen de Medeiros Pondofe3Vanessa Regiane Resqueti4Luciana Protásio de Melo5Ricardo Alexsandro de Medeiros Valentim6Department of Physical Therapy and Laboratory of Technological Innovation in Health, Federal University of Rio Grande do Norte, Natal, Brazil1 Department of Physical Therapy, Federal University of Rio Grande do Norte, Natal, Brazil1 Department of Physical Therapy, Federal University of Rio Grande do Norte, Natal, Brazil1 Department of Physical Therapy, Federal University of Rio Grande do Norte, Natal, Brazil1 Department of Physical Therapy, Federal University of Rio Grande do Norte, Natal, Brazil2 Laboratory of Technological Innovation in Health, Federal University of Rio Grande do Norte, Natal, Brazil2 Laboratory of Technological Innovation in Health, Federal University of Rio Grande do Norte, Natal, BrazilIntroduction Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease with variable and complex clinical manifestations that requires a multidisciplinary approach. However, face-to-face treatment in this population may experience barriers, such as difficulty accessing physical therapists or other professionals. As a result, strategies (eg, telerehabilitation) emerged to facilitate treatment and physical therapy monitoring. This study aims to evaluate the effects of remote versus face-to-face home-based exercise programmes on clinical outcomes and treatment adherence of people with ALS.Methods and analysis This is a single-blind randomised clinical trial protocol that will include 44 people with clinical diagnosis of ALS at any clinical stage and aged between 18 and 80 years. Participants will be randomised into two groups after face-to-face evaluation and perform a home-based exercise programme three times a week for 6 months. A physical therapist will monitor the exercise programme once a week remotely (phone calls—experimental group) or face-to-face (home visits—control group). The primary outcome measure will be functional capacity (Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised). Secondary outcomes will include disease severity (Amyotrophic Lateral Sclerosis Severity Scale), fatigue (Fatigue Severity Scale), pain (Visual Analogue Scale and body pain diagram), adverse events and adherence rate. Outcomes will be initially evaluated face-to-face and revaluated remotely every 2 months and 1 month after interventions. Linear mixed models will compare outcome measures between groups and evaluations (α=5%).Ethics and dissemination This study was approved by the research ethics committee of Hospital Universitário Onofre Lopes/Universidade Federal do Rio Grande do Norte (no. 3735479). We expect to identify the effects of an exercise programme developed according to ALS stages and associated with remote or face-to-face monitoring on clinical outcomes using revaluations and follow-up after interventions.Trial registration number Brazilian Registry Clinical Trials (RBR-10z9pgfv).https://bmjopen.bmj.com/content/12/5/e056323.full |
| spellingShingle | Tatiana Souza Ribeiro Aline Alves de Souza Stephano Tomaz da Silva Karen de Medeiros Pondofe Vanessa Regiane Resqueti Luciana Protásio de Melo Ricardo Alexsandro de Medeiros Valentim Remote versus face-to-face home-based exercise programme in people with amyotrophic lateral sclerosis: protocol for a randomised clinical trial BMJ Open |
| title | Remote versus face-to-face home-based exercise programme in people with amyotrophic lateral sclerosis: protocol for a randomised clinical trial |
| title_full | Remote versus face-to-face home-based exercise programme in people with amyotrophic lateral sclerosis: protocol for a randomised clinical trial |
| title_fullStr | Remote versus face-to-face home-based exercise programme in people with amyotrophic lateral sclerosis: protocol for a randomised clinical trial |
| title_full_unstemmed | Remote versus face-to-face home-based exercise programme in people with amyotrophic lateral sclerosis: protocol for a randomised clinical trial |
| title_short | Remote versus face-to-face home-based exercise programme in people with amyotrophic lateral sclerosis: protocol for a randomised clinical trial |
| title_sort | remote versus face to face home based exercise programme in people with amyotrophic lateral sclerosis protocol for a randomised clinical trial |
| url | https://bmjopen.bmj.com/content/12/5/e056323.full |
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