Effect of Polypropylene Microplastic and Florfenicol Antibiotic on Some Hormonal and Haematological Biomarkers in Yellowfin Seabream (Acanthopagrus latus)
Microplastics (MPs) and antibiotics, such as florfenicol (FFC), are emerging pollutants affecting aquatic ecosystems. This research examined the separate and joint impacts of MPs and FFC on hematological and hormonal indicators in yellowfin seabream (Acanthopagrus latus). The fish were categorized i...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Istanbul University Press
2025-04-01
|
| Series: | Aquatic Sciences and Engineering |
| Subjects: | |
| Online Access: | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/726320695250486D8F625776B85D8637 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849313065290432512 |
|---|---|
| author | Mehrnaz Shirmohammadi Farahnaz Kianersi Nima Shiry Fatemeh Hekmatpour |
| author_facet | Mehrnaz Shirmohammadi Farahnaz Kianersi Nima Shiry Fatemeh Hekmatpour |
| author_sort | Mehrnaz Shirmohammadi |
| collection | DOAJ |
| description | Microplastics (MPs) and antibiotics, such as florfenicol (FFC), are emerging pollutants affecting aquatic ecosystems. This research examined the separate and joint impacts of MPs and FFC on hematological and hormonal indicators in yellowfin seabream (Acanthopagrus latus). The fish were categorized into four groups according to their dietary treatments: a control group with a standard diet and three experimental groups receiving diets containing 15 mg/kg of FFC, 100 mg/kg of MPs, or both for 10-day. The ELISA method was used to measure hormones in plasma. Blood collection occurred on the first, fourth, seventh, and fourteenth days after feeding stopped to evaluate FFC concentration in the plasma and various hematological and hormonal parameters. Exposure to FFC and MPs, alone or together, considerably decreased red blood cell, hemoglobin levels, hematocrit values, mean corpuscular hemoglobin, mean corpuscular hemoglobin, white blood cell, lymphocyte, and erythropoietin concentrations. Neutrophil and cortisol levels increased. Mean corpuscular volume was elevated only in the group receiving both FFC and MPs. After a 14- day recovery period, all measured parameters returned to baseline levels in the FFC-only group. Co-exposed group showed the highest concentration of FFC in the plasma on the first day. The groups administered MPs, individually or collectively, exhibited a reduction in thyroid hormones. These findings indicate that both MPs and FFC induce anemia and stress in yellowfin seabream, with co-exposure exacerbating these effects. Although the toxic effects of FFC were temporary, the lasting presence of MPs indicates potential long-term risks. |
| format | Article |
| id | doaj-art-8d1e172690a0468abd07d5a355d0a37b |
| institution | Kabale University |
| issn | 2602-473X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Istanbul University Press |
| record_format | Article |
| series | Aquatic Sciences and Engineering |
| spelling | doaj-art-8d1e172690a0468abd07d5a355d0a37b2025-08-20T03:52:52ZengIstanbul University PressAquatic Sciences and Engineering2602-473X2025-04-0140211612310.26650/ASE20251638853123456Effect of Polypropylene Microplastic and Florfenicol Antibiotic on Some Hormonal and Haematological Biomarkers in Yellowfin Seabream (Acanthopagrus latus)Mehrnaz Shirmohammadi0https://orcid.org/0009-0003-7140-0626Farahnaz Kianersi1https://orcid.org/0009-0001-3956-7990Nima Shiry2https://orcid.org/0000-0002-7838-269XFatemeh Hekmatpour3https://orcid.org/0000-0002-1184-5143South of Iran Aquaculture Research Institute, Ahvaz, IranSouth of Iran Aquaculture Research Institute, Ahvaz, IranPersian Gulf and Oman Sea Ecological Research Institute, Bandar-Abbas, IranSouth of Iran Aquaculture Research Institute, Ahvaz, IranMicroplastics (MPs) and antibiotics, such as florfenicol (FFC), are emerging pollutants affecting aquatic ecosystems. This research examined the separate and joint impacts of MPs and FFC on hematological and hormonal indicators in yellowfin seabream (Acanthopagrus latus). The fish were categorized into four groups according to their dietary treatments: a control group with a standard diet and three experimental groups receiving diets containing 15 mg/kg of FFC, 100 mg/kg of MPs, or both for 10-day. The ELISA method was used to measure hormones in plasma. Blood collection occurred on the first, fourth, seventh, and fourteenth days after feeding stopped to evaluate FFC concentration in the plasma and various hematological and hormonal parameters. Exposure to FFC and MPs, alone or together, considerably decreased red blood cell, hemoglobin levels, hematocrit values, mean corpuscular hemoglobin, mean corpuscular hemoglobin, white blood cell, lymphocyte, and erythropoietin concentrations. Neutrophil and cortisol levels increased. Mean corpuscular volume was elevated only in the group receiving both FFC and MPs. After a 14- day recovery period, all measured parameters returned to baseline levels in the FFC-only group. Co-exposed group showed the highest concentration of FFC in the plasma on the first day. The groups administered MPs, individually or collectively, exhibited a reduction in thyroid hormones. These findings indicate that both MPs and FFC induce anemia and stress in yellowfin seabream, with co-exposure exacerbating these effects. Although the toxic effects of FFC were temporary, the lasting presence of MPs indicates potential long-term risks.https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/726320695250486D8F625776B85D8637yellowfin seabreamacanthopagrus latusflorfenicolhaematological/ hormonal indicesmicroplastics |
| spellingShingle | Mehrnaz Shirmohammadi Farahnaz Kianersi Nima Shiry Fatemeh Hekmatpour Effect of Polypropylene Microplastic and Florfenicol Antibiotic on Some Hormonal and Haematological Biomarkers in Yellowfin Seabream (Acanthopagrus latus) Aquatic Sciences and Engineering yellowfin seabream acanthopagrus latus florfenicol haematological/ hormonal indices microplastics |
| title | Effect of Polypropylene Microplastic and Florfenicol Antibiotic on Some Hormonal and Haematological Biomarkers in Yellowfin Seabream (Acanthopagrus latus) |
| title_full | Effect of Polypropylene Microplastic and Florfenicol Antibiotic on Some Hormonal and Haematological Biomarkers in Yellowfin Seabream (Acanthopagrus latus) |
| title_fullStr | Effect of Polypropylene Microplastic and Florfenicol Antibiotic on Some Hormonal and Haematological Biomarkers in Yellowfin Seabream (Acanthopagrus latus) |
| title_full_unstemmed | Effect of Polypropylene Microplastic and Florfenicol Antibiotic on Some Hormonal and Haematological Biomarkers in Yellowfin Seabream (Acanthopagrus latus) |
| title_short | Effect of Polypropylene Microplastic and Florfenicol Antibiotic on Some Hormonal and Haematological Biomarkers in Yellowfin Seabream (Acanthopagrus latus) |
| title_sort | effect of polypropylene microplastic and florfenicol antibiotic on some hormonal and haematological biomarkers in yellowfin seabream acanthopagrus latus |
| topic | yellowfin seabream acanthopagrus latus florfenicol haematological/ hormonal indices microplastics |
| url | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/726320695250486D8F625776B85D8637 |
| work_keys_str_mv | AT mehrnazshirmohammadi effectofpolypropylenemicroplasticandflorfenicolantibioticonsomehormonalandhaematologicalbiomarkersinyellowfinseabreamacanthopagruslatus AT farahnazkianersi effectofpolypropylenemicroplasticandflorfenicolantibioticonsomehormonalandhaematologicalbiomarkersinyellowfinseabreamacanthopagruslatus AT nimashiry effectofpolypropylenemicroplasticandflorfenicolantibioticonsomehormonalandhaematologicalbiomarkersinyellowfinseabreamacanthopagruslatus AT fatemehhekmatpour effectofpolypropylenemicroplasticandflorfenicolantibioticonsomehormonalandhaematologicalbiomarkersinyellowfinseabreamacanthopagruslatus |