Blood plasma proteome-wide association study implicates novel proteins in the pathogenesis of multiple cardiovascular diseases

Blood plasma proteome-wide association study implicates novel proteins in the pathogenesis of multiple cardiovascular diseases

Abstract Background Cardiovascular diseases (CVD) are the leading cause of global mortality, yet current treatments benefit only a subset of patients. To identify new potential treatment targets, we conducted the first proteome wide association study (PWAS) for 26 CVDs using plasma proteomics data f...

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Bibliographic Details
Main Authors: Jia-Hao Wang, Shan-Shan Dong, Wei Huang, Hao-An Wang, Shao-Shan Liu, Xiaoyi Ma, Ren-Jie Zhu, Wei Shi, Hao Wu, Ke Yu, Tian-Pei Zhang, Cong-Ru Wang, Yan Guo, Hanzhong Xue, Tie-Lin Yang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Cardiovascular Diabetology
Subjects:
CVD
Human blood plasma proteomes
Causal proteins
PWAS
Online Access:https://doi.org/10.1186/s12933-025-02847-w
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