A Clinico-Demographic Study of Mucormycosis Cases Admitted in a Tertiary Care Government Hospital in Western Maharashtra
Background: Mucormycosis, caused by filamentous fungi, is a rare but potentially fatal fungal infection associated with high morbidity and mortality. The COVID-19 pandemic has brought renewed attention to this infection, with an increasing number of cases worldwide. To study the clinico-demographic...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-07-01
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| Series: | Indian Journal of Community Medicine |
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| Online Access: | https://journals.lww.com/10.4103/ijcm.ijcm_137_24 |
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| author | MS Anitha Sagar Mitrajit Gaikwad Gajanan M. Jatti Lagdir L. Gaikwad Hemlata G. Rokade Wasim A. Bennishirur |
| author_facet | MS Anitha Sagar Mitrajit Gaikwad Gajanan M. Jatti Lagdir L. Gaikwad Hemlata G. Rokade Wasim A. Bennishirur |
| author_sort | MS Anitha |
| collection | DOAJ |
| description | Background:
Mucormycosis, caused by filamentous fungi, is a rare but potentially fatal fungal infection associated with high morbidity and mortality. The COVID-19 pandemic has brought renewed attention to this infection, with an increasing number of cases worldwide. To study the clinico-demographic characteristics and their association with outcomes in mucormycosis cases. A tertiary care government hospital in Western Maharashtra. A Descriptive Cross-Sectional study.
Methodology:
The study was conducted in a tertiary care hospital analyzing information from all cases of mucormycosis admitted between January 2021 and December 2022. Data were collected from the medical record section encompassing demographic details, clinical features, treatment, and outcome. Proportion, standard deviation, Chi-square test were used to analyze data by using Microsoft Excel.
Results:
Demographic analysis revealed a predominance of males 66.67%, and rural residents 73.53% among the mucormycosis cases. Co-morbidities were prevalent in 71.57% cases. The most common clinical presentation was rhino-orbital-cerebral mucormycosis (91.67%). Cortico-steroid use was seen in 58.82% cases. Among 270 cases, the case fatality rate was 24.45%. Older age, co-morbidities, COVID-19 status, delayed diagnosis, and delay in treatment were significantly associated with mortality.
Conclusions:
Demographic, clinical, and treatment-related factors influence mucormycosis outcome. Early diagnosis, aggressive treatment, and management of co-morbidities can mitigate morbidity and mortality associated with mucormycosis. |
| format | Article |
| id | doaj-art-8d19359a64c14de9a66f08b214477c72 |
| institution | DOAJ |
| issn | 0970-0218 1998-3581 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Community Medicine |
| spelling | doaj-art-8d19359a64c14de9a66f08b214477c722025-08-20T02:56:48ZengWolters Kluwer Medknow PublicationsIndian Journal of Community Medicine0970-02181998-35812025-07-0150466366810.4103/ijcm.ijcm_137_24A Clinico-Demographic Study of Mucormycosis Cases Admitted in a Tertiary Care Government Hospital in Western MaharashtraMS AnithaSagar Mitrajit GaikwadGajanan M. JattiLagdir L. GaikwadHemlata G. RokadeWasim A. BennishirurBackground: Mucormycosis, caused by filamentous fungi, is a rare but potentially fatal fungal infection associated with high morbidity and mortality. The COVID-19 pandemic has brought renewed attention to this infection, with an increasing number of cases worldwide. To study the clinico-demographic characteristics and their association with outcomes in mucormycosis cases. A tertiary care government hospital in Western Maharashtra. A Descriptive Cross-Sectional study. Methodology: The study was conducted in a tertiary care hospital analyzing information from all cases of mucormycosis admitted between January 2021 and December 2022. Data were collected from the medical record section encompassing demographic details, clinical features, treatment, and outcome. Proportion, standard deviation, Chi-square test were used to analyze data by using Microsoft Excel. Results: Demographic analysis revealed a predominance of males 66.67%, and rural residents 73.53% among the mucormycosis cases. Co-morbidities were prevalent in 71.57% cases. The most common clinical presentation was rhino-orbital-cerebral mucormycosis (91.67%). Cortico-steroid use was seen in 58.82% cases. Among 270 cases, the case fatality rate was 24.45%. Older age, co-morbidities, COVID-19 status, delayed diagnosis, and delay in treatment were significantly associated with mortality. Conclusions: Demographic, clinical, and treatment-related factors influence mucormycosis outcome. Early diagnosis, aggressive treatment, and management of co-morbidities can mitigate morbidity and mortality associated with mucormycosis.https://journals.lww.com/10.4103/ijcm.ijcm_137_24co-morbiditycovid-19mucormycosis |
| spellingShingle | MS Anitha Sagar Mitrajit Gaikwad Gajanan M. Jatti Lagdir L. Gaikwad Hemlata G. Rokade Wasim A. Bennishirur A Clinico-Demographic Study of Mucormycosis Cases Admitted in a Tertiary Care Government Hospital in Western Maharashtra Indian Journal of Community Medicine co-morbidity covid-19 mucormycosis |
| title | A Clinico-Demographic Study of Mucormycosis Cases Admitted in a Tertiary Care Government Hospital in Western Maharashtra |
| title_full | A Clinico-Demographic Study of Mucormycosis Cases Admitted in a Tertiary Care Government Hospital in Western Maharashtra |
| title_fullStr | A Clinico-Demographic Study of Mucormycosis Cases Admitted in a Tertiary Care Government Hospital in Western Maharashtra |
| title_full_unstemmed | A Clinico-Demographic Study of Mucormycosis Cases Admitted in a Tertiary Care Government Hospital in Western Maharashtra |
| title_short | A Clinico-Demographic Study of Mucormycosis Cases Admitted in a Tertiary Care Government Hospital in Western Maharashtra |
| title_sort | clinico demographic study of mucormycosis cases admitted in a tertiary care government hospital in western maharashtra |
| topic | co-morbidity covid-19 mucormycosis |
| url | https://journals.lww.com/10.4103/ijcm.ijcm_137_24 |
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